Low-Calorie Vegetable Food Preparations for Cancer Metabolic Support
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Solution Overview
Problem
Existing diets for cancer patients undergoing anticancer treatments lack a balanced, biologically active, and well-tolerated approach to modulate metabolic pathways, impacting tumor growth and enhancing therapeutic efficacy.
Innovation Solution
A low-calorie, low-carbohydrate, and low-protein diet plan comprising specific nutritional combinations and vegetable-derived food preparations, designed to reduce glucose and insulin levels, acting as a therapeutic adjuvant to anticancer therapies.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a low-calorie, low-carbohydrate, and low-protein diet is implemented, then metabolic effects are enhanced (reduced glucose and insulin levels, stimulated anticancer lymphocyte populations), but the nutritional adequacy for cancer patients may be compromised
Solution Approach 1:
The patent applies parameter changes by precisely controlling the caloric content (15-600 Kcal/day), carbohydrate content (8-55% w/w), protein content (7-16% w/w), and lipid content (30-81% w/w) of the diet. These specific parameter ranges create the desired metabolic effects (reduced glucose and insulin levels, increased anticancer lymphocyte activity) while maintaining nutritional adequacy through controlled nutrient composition rather than simple calorie restriction alone
2Reliability
If the diet composition is optimized for metabolic effects, then anticancer response is enhanced, but the complexity of diet design and implementation increases
Solution Approach 1:
The patent segments the diet into specific daily food preparations with defined macronutrient compositions and caloric contents. By dividing the overall dietary intervention into discrete, standardized meal components (breakfast, lunch, dinner, snacks) with specific nutritional parameters, the complex metabolic goals are achieved through manageable, structured dietary units that simplify implementation while maintaining efficacy
3Reliability
If calorie restriction is applied to reduce tumor incidence, then tumor growth is suppressed, but patient tolerance and acceptance of the diet may decrease
Solution Approach 1:
The patent applies dynamics by allowing flexible adjustment of caloric intake within the 15-600 Kcal/day range based on individual patient needs, treatment phase, and tolerance. The diet can be dynamically modified during the three-week or four-week treatment cycles, and can be adapted for use before, during, and after anticancer treatments, making the restrictive diet more acceptable and sustainable for patients while maintaining tumor suppression effects
Data Source
AI summary
Daily food preparation for use as a therapeutic adjuvant in the diet of patients suffering from neoplasia, including A) a nutritional combination that contains carbohydrates in an amount between 8% and 55% (w/w), proteins in an amount between 7% and 16 % (w/w), lipids in an amount between 30% and 81% (w/w); and B) dietary fiber in an amount between 2 and 30 g, the food preparation being characterized by an average caloric content between 15 and 600 Kcal, in which the nutritional combination (A) and the dietary fiber (B) consist of foods of vegetable origin. A further object of the present invention is a kit comprising daily food preparations in accordance with claim 1 for use as a therapeutic adjuvant in the daily diet of patients suffering from neoplasias.