Low-Concentration Perfume Compositions for Synergistic Antimicrobial Action
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
There is a need for antimicrobial compositions that provide effective antimicrobial activity with minimal impact on the perfume profile and reduce the risk of microbial resistance, while using lower concentrations of ingredients.
Innovation Solution
Compositions containing specific perfume ingredients such as heliopropanal, nerol, phenylhexanol, and tetralinol, or combinations like anisic aldehyde, heliotropin, and terpineol, are formulated to achieve synergistic antimicrobial effects at low concentrations, effectively inactivating bacterial cells without significantly altering the odor profile.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If large amounts of perfuming ingredients are used to deliver antimicrobial properties, then antimicrobial activity is improved, but the odor profile of the end-product is strongly influenced and use is limited
Solution Approach 1:
The patent changes the concentration parameter of perfuming ingredients from high (50% or more) to low (0.01-10%, preferably 0.05-5%), thereby achieving antimicrobial activity while minimizing impact on odor profile. This parameter change resolves the contradiction between effective antimicrobial action and acceptable product odor.
Solution Approach 2:
The patent uses composite formulations combining multiple perfuming ingredients (aldehydes, alcohols, esters, ketones) in specific ratios to achieve synergistic antimicrobial effects at low concentrations. This composite approach allows enhanced antimicrobial activity without requiring high doses of individual ingredients, thus preserving the desired odor profile.
2Reliability
If higher concentrations of bioactive ingredients are used, then antimicrobial efficacy is improved, but the risk of microbial resistance increases
Solution Approach 1:
The patent employs low concentration parameters (0.01-10% of perfuming ingredients) to achieve antimicrobial activity, which reduces the selective pressure that drives microbial resistance development while maintaining sufficient efficacy through synergistic combinations.
Solution Approach 2:
The patent formulates composite mixtures of multiple perfuming ingredients with different chemical structures and mechanisms of action (aldehydes, alcohols, esters, ketones). This multi-component composite approach reduces resistance risk by targeting multiple microbial pathways simultaneously, making it harder for microbes to develop resistance compared to single high-concentration agents.
3Object-generated harmful factors
If perfume ingredients are used as antimicrobial agents, then the need for traditional biocides is reduced, but the concentration required for effective antimicrobial action may increase
Solution Approach 1:
The patent creates composite formulations combining four types of perfuming ingredients (aldehydes, alcohols, esters, and ketones) in specific ratios. This composite structure produces synergistic antimicrobial effects that enhance potency, allowing effective antimicrobial action at low concentrations (0.01-10%) rather than high concentrations.
Solution Approach 2:
The patent optimizes the concentration parameter to a low range (0.01-10%, preferably 0.05-5%) through synergistic formulation, achieving effective antimicrobial activity without requiring high doses. This low-concentration parameter change reduces side effects while maintaining efficacy.
Data Source
AI summary
The various aspects presented herein relate to the field of antimicrobial compositions and their use as antibacterial agents, or their use for the preparation of antimicrobially active perfuming compositions and consumer products.