Low-Dose Lectin Composition for Efficacy With Fewer Side Effects

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Solution Overview

Problem

Existing lectin compositions for cancer treatment and drug side effect management suffer from high doses leading to intolerances and side effects, negatively impacting patient compliance and therapy success.

Innovation Solution

A lectin composition with reduced doses (0.2 to 0.04 mg daily) combined with selenium, proteolytic enzymes, and other additives, formulated in various forms for oral administration, minimizing side effects while maintaining efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high doses of lectins (5-100 mg daily) are administered, then therapeutic efficacy is improved, but side effects and intolerances increase

Engineering Contradiction:
Improvetherapeutic efficacyVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by optimizing the lectin dosage to a specific range (0.5-10 mg daily, preferably 1-5 mg) rather than using high doses (5-100 mg). This dosage optimization resolves the contradiction by finding the optimal parameter value that provides sufficient therapeutic efficacy while minimizing side effects and intolerances

Inventive Principle:
Principle #35Parameter changes

2Reliability

If high doses of lectins are used, then treatment results improve, but patient compliance decreases due to intolerances

Engineering Contradiction:
Improvetreatment resultsVSAvoidpatient compliance
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

By changing the dosage parameter to an optimized range (0.5-10 mg daily), the patent simultaneously improves patient compliance and maintains treatment results, resolving the contradiction between efficacy and ease of operation

Inventive Principle:
Principle #35Parameter changes

3Reliability

If lectin concentration is increased, then effectiveness improves, but side effects increase

Engineering Contradiction:
ImproveeffectivenessVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent optimizes the lectin concentration parameter to a specific range that maximizes effectiveness while minimizing harmful side effects, directly resolving the contradiction between these two opposing factors

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3978006B1Composition with optimized lectin content and its use
Publication Date: 2025.11.05 YACARE GMBH
  • EP3978006B1 patent drawingFigure 1
  • EP3978006B1 patent drawingFigure 2
  • EP3978006B1 patent drawingFigure 3

AI summary

The invention relates to a composition comprising at least one lectin-containing lentil extract and/or lectin-containing pea extract, wherein the lentil lectin and/or pea lectin content is 0.1 to 0.03 mg, preferably 0.2 to 0.04 mg, particularly preferably 0.5 to 0.08 mg, and optionally further additives and excipients.