Low-Energy Irradiation Data Planning for Tumor Treatment

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Solution Overview

Problem

Current methods for tumor treatment using radiation therapy are not applicable to low-energy irradiation systems, as they fail to accurately calculate and adjust the irradiation dose due to complex interactions between low-energy radiation and tissue, leading to deviations from true dose values.

Innovation Solution

A method for generating and providing data for tissue treatment using a low-energy irradiation system, which involves determining physical data of the radiation source and quality data of the tissue, calculating the dose rate, and visually displaying treatment planning data on a display screen, allowing for direct and accurate planning of tumor treatment with low-energy radiation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If linear accelerator methods are used for irradiation planning, then accurate dose calculation is achieved, but the method is not applicable to low-energy irradiation systems

Engineering Contradiction:
Improveapplicability to low-energy systemsVSAvoiddose calculation accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent changes the fundamental parameters of the irradiation system from high-energy linear accelerators to low-energy systems (maximal energy 100 keV, preferably 50 keV). This requires adapting the planning method to account for different physical interactions (photoelectric effect, Compton effect) that dominate at low energies, thereby resolving the contradiction between system adaptability and measurement precision

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent performs preliminary determination of the radiation spectrum directly at the emitting device before irradiation. By measuring or calculating the spectrum characteristics in advance and using them for dose rate calculations, the method ensures accurate dose planning specific to low-energy systems, thus maintaining precision while adapting to different energy levels

Inventive Principle:
Principle #10Preliminary action

2Use of energy by moving object

If low-energy radiation is used for irradiation, then complex physical interactions with tissue occur, but the known planning procedures cannot be applied

Engineering Contradiction:
Improveradiation energy levelVSAvoidplanning procedure complexity
Core Design Contradiction:
Use of energy by moving objectVSDevice complexity

Solution Approach 1:

The patent introduces an intermediary step of determining the radiation spectrum characteristics as a mediator between the low-energy radiation source and the dose calculation. This spectrum determination serves as a bridge that translates the complex physical interactions into usable planning data, simplifying the overall procedure while maintaining accuracy

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical/physical complexity of understanding all low-energy interactions with a computational approach. By using calculated or measured spectrum data to inform dose rate calculations, the method substitutes direct physical measurement and complex interaction modeling with a more manageable computational procedure

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-affected harmful factors

If low-energy rays are used for irradiation, then different tissue types weaken rays to different degrees, but accurate dose determination becomes difficult

Engineering Contradiction:
Improvetissue attenuation effectsVSAvoiddose rate determination accuracy
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The patent applies local quality by determining the radiation spectrum specifically at each emitting device and using tissue-specific attenuation characteristics for different tissue types. By accounting for the unique properties of each tissue type along the radiation path and their differential attenuation effects, the method achieves accurate dose rate determination despite varying tissue compositions

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate and visual planning of tissue treatment with low-energy irradiation systems, ensuring the physical and biological effectiveness of the treatment by calculating and displaying dose rates and other relevant data, thereby addressing the limitations of existing methods.

Implementation Method 1

the so called photo- or Compton-effect (see WO 2010/011844)

Methodology Applied
Scientific EffectPhotoelectric effect: Photoelectric Effect

Implementation Method 2

the so called photo- or Compton-effect (see WO 2010/011844)

Methodology Applied
Scientific EffectCompton effect: Compton Scattering

Data Source

PatentEP2569053B1Method of generating and/or providing data for tissue treatment
Publication Date: 2018.11.14 CARL ZEISS MEDITEC AG
  • EP2569053B1 patent drawingFigure 1
  • EP2569053B1 patent drawingFigure 2
  • EP2569053B1 patent drawingFigure 3

AI summary

A method of generating and/or providing data (28) for tissue treatment, in particular a tumor treatment, via a low-energy irradiation appliance (10) is described. Herein, the low-energy irradiation appliance (10) has a radiation source (14) for generating soft radiation, preferably of a radiation with a spectrum from 0 to a maximal radiation energy of 100keV, in particular a radiation with a spectrum from 0 to a maximal radiation energy of 50keV and an emitting device (15) for emitting the radiation to tissue, which is to be irradiated. The method is characterized by the following steps: physical data of the radiation source (14) is determined directly from leaving the emitting device (15); quality data of the tissue, for example the tumor tissue and/or the tissue (17) in the vicinity of the tumor, is determined; physical property data of the determined tissue is determined in connection with the radiation of the radiation source (14). Data (28) for the tissue treatment, for example the tumor treatment, is generated from the determined data and/or the determined data is provided for generating data for the tissue treatment, in particular tumor treatment.