Low Melt Flow Polypropylene Resins for Medical Vials

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Solution Overview

Problem

Existing methods for two-stage injection-stretch-blow-moulding processes do not produce medical vials with an ideal balance of properties, including optical, thickness distribution, stacking, and drop test performance, especially at low temperatures.

Innovation Solution

The use of low melt flow polypropylene resins with a Ziegler-Natta catalyst system, specifically random copolymers of propylene and ethylene with a melt flow index of 1 to 3 dg/min, and an injection temperature of at least 280°C, along with optimized injection-stretch-blow-moulding conditions, to produce preforms for medical vials with improved properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional polypropylene resins with higher melt flow index are used in two-stage injection-stretch-blow-moulding, then the processing is easier and injection temperature can be lower, but the resulting medical vials do not achieve ideal balance of optical properties, thickness distribution, stacking properties, and drop test performance

Engineering Contradiction:
Improvethickness distributionVSAvoidinjection temperature
Core Design Contradiction:
Manufacturing precisionVSTemperature

Solution Approach 1:

The patent changes the melt flow index parameter from conventional values (typically 5-50 dg/min) to a specific low range (1-3 dg/min), which fundamentally alters the processing requirements and enables achievement of ideal thickness distribution and optical properties through precise control at elevated temperatures

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent utilizes the phase transition behavior of the low melt flow polypropylene resin at elevated temperatures (≥280°C) to achieve optimal melting and filling characteristics during injection moulding, enabling precise control of the melting phase for uniform thickness distribution

Inventive Principle:
Principle #36Phase transitions

2Illumination intensity

If conventional polypropylene resins are used, then processing conditions can be maintained at standard temperatures, but the medical vials exhibit poor optical properties and insufficient stacking performance

Engineering Contradiction:
Improveoptical propertiesVSAvoidprocessing conditions
Core Design Contradiction:
Illumination intensityVSEase of manufacture

Solution Approach 1:

The patent changes the melt flow index parameter from conventional values (typically 5-50 dg/min) to a specific low range (1-3 dg/min), which fundamentally alters the processing requirements and enables achievement of ideal thickness distribution and optical properties through precise control at elevated temperatures

Inventive Principle:
Principle #35Parameter changes

3Strength

If standard injection moulding is used with conventional resins, then production efficiency is maintained, but the medical vials fail to achieve superior impact strength and drop test performance

Engineering Contradiction:
Improveimpact strengthVSAvoidinjection cavity fill rate
Core Design Contradiction:
StrengthVSQuantity of substance

Solution Approach 1:

The patent changes the melt flow index parameter from conventional values (typically 5-50 dg/min) to a specific low range (1-3 dg/min), which fundamentally alters the processing requirements and enables achievement of ideal thickness distribution and optical properties through precise control at elevated temperatures

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The resulting medical vials exhibit excellent optical properties, uniform wall thickness distribution, superior impact strength, and enhanced stacking and drop test performance, making them suitable for medical applications and potentially replacing glass bottles.

Implementation Method 1

the polypropylene resin used in the present invention is prepared with a Ziegler-Natta (ZN) catalyst system

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 2

The injection temperatures cited in the examples are of 230 and 240° C. Preferably, the polypropylene resin used in the present invention is prepared with a Ziegler-Natta (ZN) catalyst system. The injection temperature for preparing the preform is of at least 280° C.

Methodology Applied
Scientific EffectMelting: Melting

Implementation Method 3

the use of low melt flow polypropylene resins for preparing preforms for injection-stretch-blow-moulding in order to prepare medical vials having excellent optical properties after bi-orientation

Methodology Applied
Scientific EffectOrientation:

Data Source

PatentUS8894911B2Low melt flow index resins for injections-stretch-blow-moulding
Publication Date: 2014.11.25 TOTAL RES & TECH FELUY SA

AI summary

The present invention discloses a method for preparing vials, preferably medical vials by two-stage injection-stretch-blow-molding with a random copolymer of propylene having a melt index MI2 of from 1 to 3 dg/min and an ethylene content of from 2 to 3.5 wt % based on the weight of the resin, and wherein the preform injection temperature is of at least 280° C.