Lysine Feed Additive Granulation via Surfactant

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Solution Overview

Problem

Current methods for producing L-lysine monohydrochloride from fermentation broths are complex and generate by-products, leading to low bulk density in granulated animal feed additives, which increases transport costs and storage issues due to dust abrasion and low packing volume.

Innovation Solution

Adding a surface-active component to the fermentation broth before spray-drying to enhance bulk density and granulation properties, resulting in a more compact and energy-efficient granule production process.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of stationary object

If fermentation broth is spray-dried to produce granulated feed additive, then amino acid supplementation is achieved, but bulk density remains low resulting in increased transport costs and storage issues

Engineering Contradiction:
Improvebulk densityVSAvoidtransport and storage efficiency
Core Design Contradiction:
Volume of stationary objectVSEase of manufacture

Solution Approach 1:

The invention changes physical parameters during spray-drying by optimizing drying conditions (temperature, airflow, spray rate) and chemical parameters (pH adjustment to 5.0-7.0, addition of divalent metal salts) to transform the fermentation broth into granules with significantly improved bulk density, directly resolving the contradiction between achieving amino acid supplementation and improving transport efficiency

Inventive Principle:
Principle #35Parameter changes

2Object-generated harmful factors

If conventional spray-drying is used without additives, then processing is simple, but dust abrasion occurs during subsequent handling

Engineering Contradiction:
Improvedust formationVSAvoidprocessing complexity
Core Design Contradiction:
Object-generated harmful factorsVSDevice complexity

Solution Approach 1:

The invention introduces divalent metal salts (calcium, magnesium, or zinc salts) as intermediary substances that act as binding agents during spray-drying. These salts bridge particles together, forming cohesive granules that resist dust formation during handling, while maintaining relatively simple processing by incorporating the additive directly into the fermentation broth before drying

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of substance

If pure L-lysine monohydrochloride is produced through separation and crystallization, then high purity is achieved, but complex method steps generate large amounts of by-products and waste

Engineering Contradiction:
Improveby-products and wasteVSAvoidpurity of L-lysine
Core Design Contradiction:
Loss of substanceVSManufacturing precision

Solution Approach 1:

The invention allows the fermentation broth to serve its own purpose as a feed additive without requiring complete purification. By adjusting pH and adding divalent metal salts, the crude broth is transformed into a stable, usable granulated product that maintains nutritional value while minimizing waste. This self-service approach converts what would be waste streams into the final product, dramatically reducing by-products and waste generation

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The addition of a surface-active substance increases the bulk density of the granulated product, reduces residual moisture, and improves granulation efficiency, leading to a more compact structure and higher spray rates during drying, thus addressing the issues of low bulk density and dust formation.

Implementation Method 1

a comparatively high bulk density of the product may be achieved and at the same time the granulation properties can be improved by the addition of a surface-active component to the fermentation broth before carrying out the spray-drying

Methodology Applied
Scientific EffectSurface tension reduction: Surfactant

Implementation Method 2

a fermentation broth containing L-amino acid, which has a water content of 35 to 75% by weight and a content of surface-active substance of 0.025 to 20% by weight, is converted by drying into a particulate composition

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS11723384B2L-amino acid-containing feedstuff additive
Publication Date: 2023.08.15 EVONIK OPERATIONS GMBH
  • US11723384B2 patent drawing

AI summary

Granulated animal feed additives having high bulk density were obtained by adding a surface-active substance to a fermentation broth containing amino acid before spray-drying, wherein low residual moisture levels were achieved at high spray rates and low granulator temperatures.