Machine Learning Pace-Mapping for Cardiac Arrhythmia Site Detection

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Solution Overview

Problem

Conventional pace-mapping techniques for identifying cardiac arrhythmia origins are inefficient and require tedious trial and error by skilled technicians to find sites with high correlation to induced electrical activity, making accurate and efficient identification of arrhythmic conductive pathways and foci difficult.

Innovation Solution

A machine learning-based pace-mapping prediction model is trained using electrophysiological data and pace-mapping datasets to predict the degree of correlation between electrical potentials, enabling more accurate and efficient identification of cardiac arrhythmia sites.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional manual pace-mapping techniques are used to identify cardiac arrhythmia origins, then skilled technicians can obtain electrical potential signals from multiple points within the cardiac area, but the process becomes tedious and time-consuming requiring trial and error to find sites with high correlation to induced electrical activity

Engineering Contradiction:
Improveaccuracy of identifying arrhythmia originsVSAvoidtime required for pace-mapping procedure
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary computational analysis of electrical potential signals to predict which pacing sites are most likely to show high correlation with induced arrhythmia. By pre-calculating and ranking potential pacing sites based on signal characteristics, the system prepares the optimal search sequence before the actual pace-mapping procedure begins, eliminating the need for random or systematic trial-and-error approaches.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A computer system acts as an intermediary between the raw electrical potential signals and the technician's decision-making process. The system processes the complex multi-point electrical signals, computes correlation metrics, and presents interpreted results that guide the technician to the most promising pacing sites, bridging the gap between raw data and actionable insights.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If conventional manual pace-mapping techniques are used to identify cardiac arrhythmia origins, then electrical potential signals can be obtained from multiple points, but the process requires skilled technicians to perform tedious trial and error

Engineering Contradiction:
Improveaccuracy of identifying arrhythmia originsVSAvoidease of performing pace-mapping
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system enables self-service by allowing the electrical signals themselves to provide the guidance information. The computational analysis automatically extracts meaningful patterns and correlation metrics from the raw electrical potential signals, making the data self-explanatory and reducing the need for skilled interpretation. The system serves itself by processing its own input data to generate actionable outputs.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The manual mechanical process of systematic trial-and-error pace-mapping is replaced with an automated computational system. Instead of technicians manually moving the catheter and testing each site sequentially, the computer system automatically analyzes electrical signals and identifies promising sites through algorithmic processing, substituting mechanical exploration with intelligent computation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Quantity of substance

If conventional manual pace-mapping techniques are used, then comprehensive pace maps can be accumulated at 100 or more sites, but the process is inefficient and difficult

Engineering Contradiction:
Improvenumber of pace-mapping data pointsVSAvoidefficiency of pace-mapping procedure
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The system applies partial action by focusing computational resources on analyzing and processing only the most informative electrical signal characteristics rather than treating all data points equally. By identifying and emphasizing key signal features that strongly correlate with arrhythmia origins, the system achieves high diagnostic accuracy with fewer effectively utilized data points, improving efficiency without sacrificing comprehensiveness.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system transforms the raw electrical potential signals into derived parameters such as correlation metrics and likelihood scores. By changing the parameter representation from raw voltage measurements to processed correlation values, the system makes the data more meaningful and actionable, enabling faster identification of arrhythmia origins while maintaining comprehensive coverage of multiple pacing sites.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12414731B2System and method to detect and identify cardiac pace-mapping sites and pacing maneuvers
Publication Date: 2025.09.16 BIOSENSE WEBSTER (ISRAEL) LTD
  • US12414731B2 patent drawing
  • US12414731B2 patent drawing
  • US12414731B2 patent drawing

AI summary

Systems and methods are disclosed for generating a pace-mapping prediction model. Techniques are provided that utilize a training dataset associated with biometrics of patients' hearts, including electrophysiological data associated with cardiac arrhythmia, pace-mapping datasets, and correlation data measuring the degree of correlation between the pace-mapping datasets and the electrophysiological data. Based on the training dataset, the pace-mapping prediction model is trained to predict a degree of correlation between a patient's electrophysiological data and a pace-mapping dataset. Based on the predicted degree of correlation, a cardiac location in the heart of a patient is predicted as the location for the next pace-mapping. Further systems and methods are disclosed for generating a pacing maneuver prediction model. The pacing maneuver prediction model is trained to predict interval measurement based on a pacing maneuver obtained during cardiac pace-mapping.