Macro-Micrograph Fusion for Infectious Disease Prediction

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Solution Overview

Problem

Conventional methods for predicting infectious disease infections, such as the SIR model and neural networks, face challenges in accurately predicting future infections due to reliance on artificial parameter setting and inability to uncover hidden relationships within infectious disease data.

Innovation Solution

The method employs macro-micrograph fusion by acquiring macro and micro infection data for regions, constructing macro and micrographs, and using graph convolutional neural networks to fuse hidden layer information, followed by time sequence calculations and predictions using prediction networks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If conventional SIR model is used for prediction, then the method is simple to implement, but the prediction accuracy is poor due to artificial parameter setting

Engineering Contradiction:
ImproveEase of implementationVSAvoidPrediction accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical/mathematical SIR model with a deep learning-based graph neural network system. Instead of using differential equations with manually set parameters, the system uses neural networks to automatically learn infection dynamics from data, substituting traditional mathematical modeling with data-driven computational approaches.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent transforms fixed artificial parameters into dynamic learned parameters. The graph neural network automatically adjusts weights and parameters during training based on actual infection data, replacing the static parameter setting of conventional models with adaptive parameter learning.

Inventive Principle:
Principle #35Parameter changes

2Ease of manufacture

If simple neural network methods are used, then the implementation is straightforward, but the prediction accuracy is not high and results cannot be interpreted

Engineering Contradiction:
ImproveEase of implementationVSAvoidPrediction accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent segments the prediction system into multiple specialized components: graph construction modules for data organization, graph neural network modules for spatial relationship processing, and interpretation modules for generating actionable insights. This segmentation allows each component to specialize in specific tasks, improving both accuracy and interpretability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces graph structures as intermediary representations between raw infection data and prediction results. The graph neural network uses these intermediate graph representations to capture complex relationships, serving as a bridge that enables both accurate prediction and meaningful interpretation of transmission patterns.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Quantity of substance

If conventional methods are used, then the computational resources required are minimal, but the ability to uncover hidden relationships in data is insufficient

Engineering Contradiction:
ImproveComputational resourcesVSAvoidHidden relationships in data
Core Design Contradiction:
Quantity of substanceVSLoss of information

Solution Approach 1:

The patent adds a graph structure dimension to traditional time-series infection data. By representing regions as nodes and transmission relationships as edges in a graph, the system captures spatial and relational dimensions that conventional methods miss, enabling discovery of hidden transmission patterns without excessive computational overhead.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS20250132057A1Infectious disease infection prediction method, apparatus, and storage medium based on macro-micrograph fusion
Publication Date: 2025.04.24 ZHEJIANG LAB
  • US20250132057A1 patent drawing
  • US20250132057A1 patent drawing
  • US20250132057A1 patent drawing

AI summary

An infectious disease infection prediction method, an apparatus, and a storage medium based on macro-micrograph fusion are provided. The method includes: acquiring macrographs of a plurality of first regions and micrographs of second regions within a set period; inputting the macroscopic graphs and the microscopic graphs into two graph convolutional neural networks to obtain two hidden layer vectors respectively, and fusing the two hidden layer vectors to obtain fusion hidden layer information of the first regions; performing a time sequence calculation of the fusion hidden layer information to obtain time sequence hidden layer information of the first regions; inputting the time series hidden layer information into two prediction networks to obtain two prediction results, respectively, and performing fusion calculation of the two prediction results to obtain a final prediction result of infectious diseases in the first regions.