Magnesium Alloy Implant Catalyst Hydrogen Conversion

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Solution Overview

Problem

Magnesium-based biodegradable implants face issues with hydrogen gas formation during degradation, which can harm tissues and cause gas pockets, as existing methods only slow down the degradation rate without reducing the total hydrogen release.

Innovation Solution

Incorporating catalysts into magnesium or magnesium alloys to catalytically convert hydrogen gas to water or other compounds, either by dispersion within the matrix or surface treatment, utilizing platinum group metals, metal oxides, or carbides to reduce hydrogen evolution.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If magnesium-based implants are used for biodegradable applications, then mechanical stability and biocompatibility are improved, but hydrogen gas formation increases causing tissue harm and gas pockets

Engineering Contradiction:
Improvemechanical stabilityVSAvoidhydrogen gas formation
Core Design Contradiction:
StrengthVSObject-generated harmful factors

Solution Approach 1:

The patent applies catalysts (such as platinum group metals, metal oxides, or carbides) to the magnesium-based implant surface to catalytically convert the harmful hydrogen gas produced during degradation into water or other benign compounds. This transforms the harmful hydrogen evolution process into a beneficial catalytic conversion, eliminating gas pockets and tissue damage while preserving the biodegradable advantage of magnesium implants.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent creates a composite material system by combining magnesium-based alloy with catalytic materials (metal particles, oxides, or carbides). This composite structure integrates the mechanical stability of magnesium with the hydrogen-converting properties of the catalyst, achieving both structural integrity and reduced hydrogen gas formation during implant degradation.

Inventive Principle:
Principle #40Composite materials

2Productivity

If degradation rate is slowed down by alloying or surface modification, then hydrogen release rate is reduced, but total hydrogen released remains unchanged

Engineering Contradiction:
Improvedegradation rateVSAvoidtotal hydrogen release
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

Instead of merely slowing down the degradation rate through conventional alloying or surface modification, the patent introduces catalysts that actively convert the hydrogen gas produced during degradation into water. This catalytic conversion addresses the total hydrogen release issue directly, transforming harmful hydrogen into benign products while allowing the implant to maintain an appropriate degradation rate for its function.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Reliability

If conventional corrosion resistance methods are applied to magnesium implants, then degradation rate is reduced, but mechanical properties and biocompatibility are compromised

Engineering Contradiction:
Improvecorrosion resistanceVSAvoidmechanical properties
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent applies catalytic materials locally on the implant surface rather than through bulk alloying or extensive surface modification. This localized approach allows the magnesium bulk to maintain its mechanical properties and biocompatibility, while the surface catalysts specifically address the hydrogen gas formation issue during degradation, achieving corrosion resistance without sacrificing mechanical integrity.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively reduces hydrogen gas emission during implant degradation, maintaining mechanical and corrosion properties while allowing for controlled degradation rates, suitable for various medical applications including coronary stents and vascular closure devices.

Implementation Method 1

Incorporating catalysts into magnesium or magnesium alloys to catalytically convert hydrogen gas to water or other compounds

Methodology Applied
Scientific EffectCatalysis: Catalysis

Data Source

PatentEP2777724B1Composite material and uses thereof
Publication Date: 2019.01.30 ST JUDE MEDICAL COORDINATION CENT
  • EP2777724B1 patent drawingFigure 1
  • EP2777724B1 patent drawingFigure 2

AI summary

A composite material for a medical implant includes a matrix of magnesium or magnesium alloy, and a catalyst which is dispersed within the matrix. The catalyst has the capacity to reduce an amount of hydrogen gas released from the matrix when the matrix is being degraded inside the patient.