Magnesium Sulfate Buffer for Animal Footbath pH Control

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Solution Overview

Problem

Current treatments for infectious bacterial conditions and lesions in animals, such as digital dermatitis and foot rot, face challenges in maintaining the antimicrobial efficacy of metal ions in footbaths due to pH fluctuations, leading to soil toxicity and reduced effectiveness, while existing formulations lack enhanced acid/base buffering capabilities to manage these issues.

Innovation Solution

The use of an aqueous formulation solution containing at least one acid, magnesium sulfate as an acid/base buffer, and an antimicrobial agent like zinc or copper salts, which maintains the pH within a range that keeps the metal ions dissolved and effective, preventing precipitation and soil toxicity, and is applied as a footbath or topical treatment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If metal ions are used in footbath solution for antimicrobial treatment, then antimicrobial efficacy is improved, but pH fluctuations cause metal ion precipitation and soil toxicity

Engineering Contradiction:
Improveantimicrobial efficacyVSAvoidsoil toxicity and metal precipitation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an acid/base buffering system as an intermediary between the metal ions and the environment. The buffer maintains pH within the optimal range (2-6), preventing metal ion precipitation and reducing soil toxicity while preserving antimicrobial efficacy. This mediator absorbs pH fluctuations and protects the metal ions from reacting with soil components.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent controls the pH parameter of the footbath solution by adding acid/base buffers. By maintaining pH within a specific range (2-6), the solution keeps metal ions in dissolved form for antimicrobial action while preventing them from precipitating and causing soil toxicity. The buffering capacity dynamically adjusts to maintain this critical parameter.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If pH is lowered to maintain metal ion dissolution, then antimicrobial activity is preserved, but skin irritation and corrosiveness increase

Engineering Contradiction:
Improveantimicrobial activityVSAvoidskin irritation and corrosiveness
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the pH parameter to a specific range (2-6) that balances antimicrobial activity with reduced skin irritation. This controlled parameter change ensures metal ions remain dissolved for effectiveness while the acidity is sufficient to kill microbes but low enough to be tolerable for animal skin when buffered properly.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The acid/base buffer acts as a mediator that smooths out extreme pH conditions. It maintains a stable, moderately acidic environment that is effective against microbes but less irritating to skin compared to unbuffered strong acids. The buffer capacity prevents pH from dropping too low even when organic loads are present.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of substance

If footbath solution is reused to reduce waste, then environmental impact is reduced, but pH changes reduce antimicrobial effectiveness

Engineering Contradiction:
Improvewaste reductionVSAvoidantimicrobial effectiveness
Core Design Contradiction:
Loss of substanceVSReliability

Solution Approach 1:

The acid/base buffer enables continuous reuse of the footbath solution by maintaining pH within the effective range over time. As animals walk through and deposit organic material, the buffer continuously neutralizes pH changes, keeping metal ions in solution and antimicrobial throughout the reuse period, extending the solution's useful life.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The buffering system provides automatic feedback control of pH. When organic loads from animals change the pH, the buffer components react to counteract the change, automatically maintaining the pH within the optimal range without external intervention. This self-regulating mechanism ensures continued antimicrobial effectiveness during reuse.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively maintains antimicrobial properties, reduces skin irritation, promotes healing, and prevents bacterial infections by maintaining a stable pH, thereby improving animal mobility and reducing the incidence of lesions like digital dermatitis and foot rot, while minimizing environmental impact.

Implementation Method 1

magnesium sulfate as an acid/base buffer

Methodology Applied
Scientific EffectAcid/base buffering:

Implementation Method 2

maintains the pH within a range that keeps the metal ions dissolved and effective, preventing precipitation

Methodology Applied
Scientific EffectPrecipitation prevention through pH control: Precipitation

Data Source

PatentUS9107418B2Animal lesion treatment and prevention formulations and methods
Publication Date: 2015.08.18 ZOETIS SERVICES LLC
  • US9107418B2 patent drawing
  • US9107418B2 patent drawing
  • US9107418B2 patent drawing

AI summary

An illustrative embodiment of an animal lesion treatment and prevention formulation includes a quantity of water, at least one acid provided in the quantity of water and magnesium sulfate as acid/base buffer mixed in the quantity of water with the at least one acid. In some embodiments, an antimicrobial agent comprising at least one antimicrobial metal salt may be provided in the quantity of water with the at least one acid and the magnesium sulfate.