Magnesium Threonate Composition for Higher Bioavailability and GI Tolerance
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Solution Overview
Problem
Existing magnesium supplements, such as magnesium oxide, hydroxide, and organic acid salts, have low bioavailability and cause gastrointestinal side effects, failing to effectively increase magnesium levels in the body, which can lead to deficiencies associated with cognitive impairment, ADHD, and other health issues.
Innovation Solution
A magnesium composition comprising magnesium threonate with non-acidified milk components enhances bioavailability, providing a soluble and pH-balanced oral dosage form for improved absorption and cognitive function.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional magnesium supplements (oxide, hydroxide, organic acid salts) are used, then magnesium intake is provided, but bioavailability is low and gastrointestinal side effects occur
Solution Approach 1:
The patent changes the chemical form of magnesium from conventional supplements (oxide, hydroxide, organic acid salts) to magnesium threonate, which has different solubility and absorption characteristics. This parameter change in the chemical structure enables higher bioavailability and reduced gastrointestinal side effects while maintaining magnesium supplementation efficacy
Solution Approach 2:
The patent creates a composite composition combining magnesium threonate with non-acidified milk components. This composite material leverages the synergistic effects of magnesium threonate's high solubility and milk components' natural absorption enhancers, achieving superior bioavailability compared to conventional magnesium supplements alone
2Quantity of substance
If conventional magnesium supplements are used, then magnesium is provided, but absorption and cognitive benefits are insufficient
Solution Approach 1:
The patent changes the chemical form of magnesium from conventional supplements to magnesium threonate, which has different solubility and absorption characteristics. This parameter change enables higher serum magnesium levels to be achieved more efficiently, directly addressing the insufficient absorption and cognitive benefits problem
Solution Approach 2:
The patent uses non-acidified milk components as intermediaries to enhance magnesium absorption. These milk components act as natural carriers and absorption facilitators, mediating the transfer of magnesium from the supplement to the bloodstream, thereby improving both absorption efficiency and cognitive benefits
Data Source
AI summary
A composition for administration to a subject, such as oral administration to a subject, for example, has been provided. Such a composition may comprise at least one magnesium-counter ion compound. A magnesium-counter ion composition described herein may be useful for any of a variety of applications provided herein, such as maintaining, enhancing, and/or improving health, nutrition, and/or another condition of a subject, and/or cognitive, learning, and/or memory function. A magnesium-counter ion composition provided herein may be useful for administration to a subject presenting magnesium deficiency, mild cognitive impairment, Alzheimer's disease, attention deficit hyperactivity disorder, ALS, Parkinson's disease, diabetes, migraine, anxiety disorder, mood disorder, and/or hypertension. A kit, method, and other associated technology are also provided.