Magnetic Particle Analyzer Layout for Through-Port Imaging

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Solution Overview

Problem

Existing analyzing apparatuses face challenges in accurately imaging the process of magnetic particle accumulation due to the obstruction caused by magnetic field generators, which prevent the imager from capturing particles within the sensor area, leading to inaccurate measurement results.

Innovation Solution

The apparatus employs a lower magnetic field generator with a specific configuration of bar magnets around a communicating port, allowing magnetic particles to accumulate within the imager's field of view by generating a magnetic field that converges vertically and diverges upward, enabling continuous observation and accurate counting.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a flat and annular magnet is used in the magnetic field generator, then the imager can image the sensor area through the communicating port, but the magnetic particles accumulate mostly in the sensor area of the inner circumference of the magnet rather than in the center portion, making it difficult for the imager to capture the sinking process

Engineering Contradiction:
Improveimaging capabilityVSAvoidparticle accumulation position
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The magnetic field generator is divided into multiple bar magnets arranged around the communicating port, each contributing to the overall magnetic field. This segmentation allows precise control of magnetic field distribution to concentrate particles in the center while maintaining imaging capability through the port

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The magnetic field strength and direction are optimized locally around the communicating port to create a magnetic field that converges vertically and directs particles to accumulate in the center portion of the sensor area, which is within the imaging range, rather than uniformly across the entire sensor area

Inventive Principle:
Principle #3Local quality

2Power

If the magnetic field generator is placed below the sample placer, then it can generate magnetic field to sink and rise magnetic particles, but it becomes an obstacle that prevents the imager from imaging the sensor area from below

Engineering Contradiction:
Improvemagnetic field generation capabilityVSAvoidimaging capability
Core Design Contradiction:
PowerVSReliability

Solution Approach 1:

The magnetic field generator is segmented into multiple bar magnets with specific orientations around the communicating port, allowing the imager to pass through the port while the magnets generate the required magnetic field below the sample placer

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The communicating port serves as an intermediary structure that allows optical signals to pass from the imager to the sensor area while the magnetic field generator components are positioned below, resolving the spatial conflict between imaging and magnetic field generation

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration ensures that magnetic particles are accurately imaged and counted, enhancing the measurement precision of the analyzing apparatus by allowing the imager to capture particles through a communicating port, thereby improving the accuracy of detection and quantification.

Implementation Method 1

generating a magnetic field that converges vertically and diverges upward

Methodology Applied
Scientific EffectMagnetic field: Magnetic Field

Implementation Method 2

lower magnetic field generator with a specific configuration of bar magnets

Methodology Applied
Scientific EffectMagnetism: Magnetism

Data Source

PatentUS12523720B2Analyzing apparatus, magnetic field generating apparatus for analyzing apparatus, and analyzing method
Publication Date: 2026.01.13 CANON MEDICAL SYST CORP
  • US12523720B2 patent drawing
  • US12523720B2 patent drawing
  • US12523720B2 patent drawing

AI summary

An analyzing apparatus according to the present embodiment comprising: a sample placer where a cartridge is placed, the cartridge being capable of storing a sample containing a magnetic substance; an imager configured to be placed on an opposite surface side of a surface where the cartridge is placed on the sample placer and configured to image the sample by imaging from the opposite surface side; and a first magnetic field generator configured to be placed on the opposite surface side and to form a communicating port on a position corresponding to the imager and configured to generate a first magnetic field by forming a first magnetic pole around the communicating port.