Magnetic Particle Blocking Zone for Fluid Interference
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Solution Overview
Problem
Existing methods for processing fluids, such as whole blood, are hindered by interfering particles like blood cells that disturb detection processes, requiring costly and space-consuming filters for separation.
Innovation Solution
A method and device utilizing magnetic particles to create a blocking zone within a processing chamber, where magnetic particles are distributed to impede the migration of interfering particles, allowing for controlled spatial distribution and concentration, effectively filtering out or concentrating these particles without the need for conventional filters.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional filters are used to remove interfering particles, then detection accuracy is improved, but device complexity and cost increase
Solution Approach 1:
The patent extracts the interfering particles from the fluid sample using magnetic forces before detection. Magnetic particles are introduced into the sample and selectively attracted to a magnetic surface, separating them from the target analyte and enabling accurate detection without conventional filters.
Solution Approach 2:
The patent uses magnetic particles as an intermediary substance to remove interfering particles. These magnetic particles interact with both the interfering particles (through magnetic attraction) and the detection system (through magnetic field interaction), providing a mechanism for particle removal without requiring physical filters.
2Productivity
If magnetic particles are distributed in a blocking zone to impede interfering particles, then processing efficiency is improved, but device complexity increases
Solution Approach 1:
The patent applies preliminary action by pre-distributing magnetic particles in a blocking zone before the fluid sample enters the detection area. This blocking zone is created using magnetic field generation, and the magnetic particles are positioned in advance to intercept and remove interfering particles before they reach the detection surface, improving processing efficiency.
3Ease of manufacture
If magnetic particles are used to create a blocking zone, then interfering particles are removed without conventional filters, but manufacturing complexity increases
Solution Approach 1:
The patent replaces the mechanical filter system with a magnetic field-based system. Instead of using physical filters that require manufacturing and assembly, the invention uses magnetic field generation to control and distribute magnetic particles, eliminating the need for conventional filter manufacturing while introducing magnetic field control mechanisms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables efficient processing of fluids by preventing interfering particles from reaching the detection area, enhancing the accuracy and efficiency of fluid processing and detection, while eliminating the need for expensive filter units and reducing processing time.
Implementation Method 1
a magnetic field generator for generating a magnetic field in the processing chamber that distributes the magnetic particles in a blocking zone within the processing chamber
Implementation Method 2
The magnetic particles are then attracted by magnetic forces to the capture antibodies, where further binding takes place
Data Source
AI summary
The invention relates to a method and a processing device for the processing of a fluid containing interfering particles (C). Magnetic particles (MP) are added to the fluid in a processing chamber and distributed, in part, using a magnetic field to provide a blocking zone (BZ) within the processing chamber to impede or prevent such migration of the interfering particles (C) through the processing chamber. The blocking zone (BZ) hence acts as a filter element by which interfering particles (C) can for example be kept away from a detection region at the surface of the processing chamber.