Magnetic Calcium Silicate Nanostructures for Dentinal Tubule Blocking
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Solution Overview
Problem
Conventional treatments for dental hypersensitivity (DH) primarily focus on temporarily sealing dentinal tubules, leading to recurring sensitivity issues, while methods disrupting nerve impulses are not adequately addressed, necessitating a more permanent solution.
Innovation Solution
A nanostructure comprising 50 to 80% magnetic material and 20 to 50% calcium silicate, with a magnetic core and calcium silicate shell, designed to navigate and block dentinal tubules, disrupting nerve impulse transmission and promoting bone growth, combined with additives like calcium oxide for cementing blocks and regenerative capabilities.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional treatments seal dentinal tubules, then sensitivity is reduced temporarily, but sensitivity recurs over time
Solution Approach 1:
The patent replaces mechanical/chemical tubule sealing methods with a magnetic field-based approach. Magnetic nanoparticles are introduced into the dentinal tubules and held in place by magnetic fields, substituting the temporary chemical sealing mechanism with a controllable physical field that can provide long-term or permanent blockage of nerve impulse transmission.
Solution Approach 2:
The patent changes the state of the tubule blockage from temporary chemical adherence to permanent magnetic positioning. By using magnetic nanoparticles with specific magnetic properties and applying magnetic fields, the blockage parameter transitions from transient to stable, achieving long-term effectiveness without recurrence.
2Reliability
If magnetic nanoparticles are used to block dentinal tubules, then nerve impulse transmission is disrupted permanently, but the complexity of the treatment increases
Solution Approach 1:
The magnetic nanoparticles serve multiple functions: they block dentinal tubules, respond to magnetic fields for positioning, and can potentially be removed or adjusted. This multi-functionality reduces the need for separate components for delivery, positioning, and activation, thereby managing complexity while achieving permanent nerve impulse disruption.
Solution Approach 2:
The magnetic field acts as an intermediary between the treatment device and the nanoparticles. Instead of direct mechanical insertion or complex chemical bonding, the magnetic field mediates the positioning and retention of nanoparticles, simplifying the overall treatment system while achieving reliable permanent blockage.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The nanostructure provides a permanent blockage of nerve impulse signals, reducing pain and promoting tissue regeneration, offering a more effective and long-lasting solution for DH.
Implementation Method 1
a magnetic particle forms a core of the nanostructure
Implementation Method 2
calcium silicate forms a shell of the nanostructure; promoting bone growth
Data Source
AI summary
The present disclosure relates to a nanostructure containing: 50 to 80% (w/w) of a magnetic material; and 20 to 50% (w/w) of calcium silicate. The present disclosure further relates to a nanocomposite containing the nanostructure as disclosed herein with an additive. The present disclosure also provides a gel containing the nanostructure or the nanocomposite and additives, and methods thereof.