Magnetic Field Guided Positron Imaging for Low-Density Objects

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Solution Overview

Problem

Current positron emission tomography (PET) methods face challenges in accurately quantifying positron emitter density distributions, especially for large-area objects with low volume and/or low material density, as emitted positrons often escape without annihilation, leading to systematic underestimation and difficulty in correcting for escape probabilities due to limited spatial resolution.

Innovation Solution

A method and device utilizing a magnetic field to guide positrons along spiral paths, allowing for two-dimensional imaging of positron emitters without tomographic reconstruction, using a positron absorber to intercept and annihilate escaping positrons, generating 511 keV gamma quanta for detection, which enables precise quantification of positron emitter density distributions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If PET method is used for imaging large-area objects with low volume and/or low material density, then spatial distribution of positron emitters can be visualized, but positrons escape without annihilation leading to systematic underestimation of true positron emitter density

Engineering Contradiction:
Improvequantification accuracy of positron emitter densityVSAvoiddetection reliability of positron annihilation events
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

A magnetic field is introduced as an intermediary to guide escaping positrons back into the detection region. The magnetic field acts as a mediator that redirects positron trajectories without directly interacting with the positron emitter distribution, allowing escaped positrons to be recaptured and annihilated within the detection volume, thereby improving quantification accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the physical parameter of positron trajectory by applying a magnetic field. This alters the path of positrons from straight-line escape to curved trajectories that return to the object, increasing the probability of annihilation events being detected and correcting the systematic underestimation.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If magnetic field is applied to guide positrons, then positron trajectories can be controlled and imaging accuracy improved, but device complexity increases due to additional magnetic field generation requirements

Engineering Contradiction:
Improvepositron trajectory control and imaging accuracyVSAvoidmagnetic field generation system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The magnetic field system serves multiple functions: it guides positron trajectories to improve imaging accuracy, and simultaneously enables the visualization of positron escape paths. By integrating the magnetic field into the existing PET system architecture, the invention achieves enhanced functionality without proportionally increasing device complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If tomographic reconstruction methods are used for PET imaging, then three-dimensional positron emitter distribution can be obtained, but correction for positron escape probability is difficult due to limited spatial resolution

Engineering Contradiction:
Improvethree-dimensional positron emitter distribution accuracyVSAvoiddifficulty in correcting positron escape probability
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

The magnetic field is applied during the positron emission and annihilation process to prevent escape before detection occurs. This preliminary action of guiding positrons eliminates the need for post-processing corrections that would otherwise be required to account for escaped positrons, simplifying the measurement and correction process.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides improved accuracy in quantifying positron emitter distributions for objects with low annihilation probability, particularly for large-area and low-density objects, by tracing positron trajectories and intercepting escaping positrons, resulting in more precise two-dimensional images without the need for tomographic reconstruction.

Implementation Method 1

a magnetic field is generated along whose field lines emitted positrons move on spiral paths due to the Lorentz force

Methodology Applied
Scientific EffectLorentz force: Lorentz Force

Implementation Method 2

positioned in the magnetic field in such a way that it can absorb the positrons emerging from the object to be examined and following the magnetic field

Methodology Applied
Scientific EffectPositron-electron annihilation:

Data Source

PatentEP3607358B1Method and system for two dimensional imaging of positron emitter distribution of slow positron absorbing objects
Publication Date: 2023.01.04 FORSCHUNGSZENTRUM JULICH GMBH
  • EP3607358B1 patent drawingFigure 1
  • EP3607358B1 patent drawingFigure 2(a)~2(c)

AI summary

The invention relates to a method and a device for the two-dimensional imaging of a positron emitter distribution of weakly positron-absorbing objects. According to the invention, the method is characterized in that the object to be examined which contains the positron emitter is positioned in a magnetic field, and the positrons leaving the object to be examined follow the curve of the magnetic field and strike a positron absorber which is likewise positioned in the magnetic field and which, upon interacting with the positrons, allows the position where the positrons struck the positron absorber to be located. For this purpose, the object to be examined which contains the positron emitter and a positron absorber are placed in a magnetic field such that the positrons follow the curve of the magnetic field and strike the positron absorber at a position. The information obtained in this manner regarding the position where the positrons struck the positron absorber is used to image the positron emitter distribution in the object to be examined.