Magnetically Switched X-Ray Targets for Flash Radiotherapy

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Solution Overview

Problem

Radiotherapy using high-energy electromagnetic radiation often causes adverse effects to healthy tissue surrounding the target, limiting the dose that can be safely applied and the efficacy of tumor destruction.

Innovation Solution

A vacuum electron device with a controllable magnetic field generator redirects and converges an electron beam to distribute its impact across multiple targets, reducing thermal effects and allowing for precise delivery of radiation to a selected region while minimizing exposure to surrounding healthy tissue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high-energy electromagnetic radiation is used to treat cancerous tumors, then the ability to selectively damage harmful tissue is improved, but adverse effects to healthy tissue surrounding the target increase

Engineering Contradiction:
Improvetumor destruction efficacyVSAvoiddamage to healthy tissue
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system segments the radiation delivery process by using multiple electron beams from different directions, each targeting the tumor from a unique angle. This segmentation allows the tumor to be irradiated from multiple perspectives while healthy tissues receive distributed, lower-dose exposure rather than concentrated high-dose exposure from a single direction.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from conventional single-direction or limited-angle radiation to three-dimensional multi-directional beam convergence. By arranging electron accelerators and targets in three-dimensional space with magnetic field control, radiation is delivered from multiple spatial dimensions, enabling the tumor to be targeted from all angles while healthy tissues located between the beams and tumor receive minimal exposure.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Power

If the electron beam is concentrated on a single target to maximize dose delivery, then the effective dose to the tumor is improved, but thermal effects cause target failure and limit treatment duration

Engineering Contradiction:
Improvedose delivery rateVSAvoidtarget thermal load
Core Design Contradiction:
PowerVSTemperature

Solution Approach 1:

The system divides the target into multiple separate targets arranged in three-dimensional space, each receiving a portion of the total radiation dose. By switching between multiple targets using magnetic field control, the thermal load is distributed across all targets rather than concentrated on a single target, preventing thermal failure and enabling continuous operation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system employs periodic switching between multiple targets, where each target receives radiation pulses in alternating sequences. This periodic action allows targets to cool down between exposure cycles, managing thermal accumulation and preventing target failure while maintaining continuous dose delivery to the tumor through the combined effect of multiple targets.

Inventive Principle:
Principle #19Periodic action

3Object-affected harmful factors

If multiple electron beams are used to irradiate the tumor from different directions, then exposure to healthy tissue is reduced, but the complexity of the device increases

Engineering Contradiction:
Improveexposure to healthy tissueVSAvoidnumber of accelerators and targets
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The system employs a single electron accelerator that serves multiple functions by generating electron beams that can be directed to multiple different targets through magnetic field control. This multi-functional approach eliminates the need for separate accelerators for each beam direction, reducing device complexity while maintaining the ability to deliver radiation from multiple angles.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention introduces a controllable magnetic field generator as an intermediary that redirects and focuses electron beams from a single accelerator to multiple targets. This magnetic field mediator enables flexible beam direction control without requiring physical reconfiguration of the accelerator, simplifying the overall system architecture while achieving multi-directional radiation delivery.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Productivity

If the electron beam is continuously directed at the same target to maintain high dose rate, then tumor treatment efficacy is improved, but the target experiences thermal failure

Engineering Contradiction:
Improvetreatment speedVSAvoidtarget durability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system segments the target into multiple individual targets, each capable of withstanding a limited number of radiation pulses before thermal failure. By distributing the total treatment dose across multiple targets and switching between them, the system maintains high dose rate delivery while preventing any single target from exceeding its thermal tolerance, thereby ensuring continuous operation and treatment reliability.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach extends the lifespan of targets, increases the effective dose delivery to a specific region, and decreases exposure to healthy tissue, enhancing the efficacy of radiotherapy while preventing thermal failures in targets.

Implementation Method 1

A controllable magnetic field generator generates a magnetic field to change a trajectory of the electron beam

Methodology Applied
Scientific EffectMagnetic field: Magnetic Field

Implementation Method 2

A redirecting magnetic field redirects the electron beam from the first axis to a second axis

Methodology Applied
Scientific EffectLorentz force: Lorentz Force

Implementation Method 3

Targets are arranged on a circular arc and generate photons upon impact by the electron beam

Methodology Applied
Scientific EffectBremsstrahlung radiation:

Data Source

PatentUS20240285976A1Ultra-high x-ray photon radiation for flash radiotherapy
Publication Date: 2024.08.29 ACCELERAD TECHNOLOGIES INC
  • US20240285976A1 patent drawing
  • US20240285976A1 patent drawing
  • US20240285976A1 patent drawing

AI summary

Vacuum electron devices (VEDs) include an electron accelerator that generates an electron beam from an electron source along a central axis. Targets are arranged on a circular arc and generate photons upon impact by the electron beam. A controllable magnetic field generator generates a magnetic field to change a trajectory of the electron beam, including a first field region that causes the electron beam to diverge from the central axis and a second field region that causes the electron beam to converge toward the central axis to impact a selected target.