Maize Inbred 1PERC07 Breeding via Doubled Haploid Technology

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, taking from six to twelve years from the first cross to the delivery of finished seed, due to the complexity of combining desirable traits such as disease resistance, drought tolerance, and high yield.

Innovation Solution

A novel maize variety, 1PERC07, is developed, along with processes for making this variety, including crossing with other maize plants to introduce desired traits through backcross conversion, genetic manipulation, and transformation, resulting in stable, high-yielding maize plants with improved agronomic characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop new maize varieties, then desirable traits such as disease resistance, drought tolerance, and high yield can be combined, but the process takes 6-12 years from first cross to finished seed delivery

Engineering Contradiction:
Improvedesirable traits combinationVSAvoiddevelopment time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using doubled haploid technology to create inbred lines in a single generation rather than requiring multiple generations of selfing. This preliminary creation of homozygous lines accelerates the breeding process significantly, reducing the time from cross to finished seed while maintaining the reliability of trait combination.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the temporal parameter of trait combination by using molecular markers and genomic selection to evaluate and select lines at earlier stages than traditional methods. This allows breeders to make selection decisions faster, reducing overall development time while maintaining reliable trait combination through accelerated breeding cycles.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If multiple desirable traits are combined in a single variety through traditional breeding, then agronomic performance improves, but the complexity of the breeding process increases

Engineering Contradiction:
Improveagronomic performanceVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the breeding process into distinct modular steps: (1) creating doubled haploid inbred lines, (2) evaluating lines using molecular markers and genomic selection, (3) selecting lines with desirable traits, and (4) producing hybrid varieties. This segmentation reduces overall complexity by making each step more manageable and standardized, while maintaining high agronomic performance through systematic trait combination.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces molecular markers and genomic selection as intermediary tools between the breeding objectives and the actual variety development. These intermediaries simplify the complex process of tracking and combining multiple traits by providing objective, measurable criteria for selection, reducing the complexity of coordinating multiple desirable traits simultaneously.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If inbred lines are created through multiple generations of selfing, then homozygosity is achieved, but the time required for line development increases

Engineering Contradiction:
ImprovehomozygosityVSAvoidline development time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using doubled haploid technology to create homozygous inbred lines in a single generation rather than requiring multiple generations of selfing. This preliminary creation of homozygous lines accelerates the breeding process significantly, reducing the time from cross to finished seed while maintaining the reliability of trait combination.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces the mechanical process of repeated selfing (which requires multiple generations) with a biotechnological approach using doubled haploids. This substitution achieves the same homozygosity outcome much faster, reducing line development time while maintaining stable genetic composition through single-generation homozygization.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12239072B1Maize inbred 1PERC07
Publication Date: 2025.03.04 PIONEER HI BREED INTERNATIONAL INC
  • US12239072B1 patent drawing

AI summary

A novel maize variety designated 1PERC07 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 1PERC07 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 1PERC07 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 1PERC07 or a locus conversion of 1PERC07 with another maize variety.