Maize Inbred 1PUVN52 for Disease Resistance and Drought Tolerance

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Solution Overview

Problem

The development of new maize varieties is a time-consuming process that requires years to combine desirable traits such as disease resistance, drought tolerance, and high yield, posing challenges in efficiently producing stable and agronomically sound maize varieties.

Innovation Solution

The development of the novel maize variety 1PUVN52, which incorporates specific traits like male sterility, disease resistance, and drought tolerance through backcross conversion, genetic manipulation, and transformation, along with the introduction of heritable traits and cytoplasmically-inherited characteristics, to enhance genetic diversity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop new maize varieties, then desirable traits can be combined, but the process takes 6-12 years making it time-consuming

Engineering Contradiction:
Improvestability of maize varietyVSAvoidbreeding cycle duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using doubled haploid technology to create inbred lines in a single generation rather than requiring multiple generations of selfing. This preliminary creation of homozygous lines accelerates the breeding process while maintaining the stability and reliability of the final variety.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the temporal parameter of the breeding process by utilizing molecular markers and genomic selection to evaluate and select lines at earlier stages. This parameter change allows for faster evaluation cycles while maintaining breeding objectives for stable, high-yielding varieties.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If multiple desirable traits are combined in a single variety, then agronomic performance improves, but the complexity of the breeding program increases

Engineering Contradiction:
Improveyield potentialVSAvoidbreeding program complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the breeding program into distinct modules: creating inbred lines with specific traits, evaluating them using molecular markers, selecting the best lines, and then combining them in controlled crosses. This segmentation reduces overall program complexity while achieving multiple desirable traits including high yield, disease resistance, and stress tolerance.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses molecular markers and genomic selection as intermediaries between the desired traits and the actual breeding process. These intermediaries allow for efficient tracking and selection of lines with multiple desirable traits, reducing the complexity of managing and evaluating complex multi-trait combinations.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If inbred lines are created through traditional selfing, then homozygosity is achieved, but the process requires multiple generations and time

Engineering Contradiction:
Improvehomozygosity of inbred lineVSAvoidnumber of generations required
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent replaces the mechanical biological process of repeated selfing (which requires multiple generations) with a biotechnological approach using doubled haploids. This substitution achieves homozygosity in a single generation, dramatically reducing the time required to create stable inbred lines while maintaining the desired homozygous composition.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12446518B1Maize inbred 1PUVN52
Publication Date: 2025.10.21 PIONEER HI BREED INTERNATIONAL INC
  • US12446518B1 patent drawing

AI summary

A novel maize variety designated 1PUVN52 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 1PUVN52 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 1PUVN52 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 1PUVN52 or a locus conversion of 1PUVN52 with another maize variety.