Maize Inbred Line BDDC4624 Segmentation for Yield and Uniformity

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Solution Overview

Problem

The challenge in corn breeding is to develop maize plants that combine desirable traits such as high yield, disease resistance, and adaptability to various environmental conditions, while also addressing issues like reduced vigor in inbred lines and the need for specific traits in different regions of the Corn Belt.

Innovation Solution

The development of the maize variety BDDC4624, which includes a range of additional traits that can be introduced through transgenes, such as increased water stress resistance, herbicide resistance, and disease resistance, allowing for the creation of hybrids and inbred lines with improved performance and adaptability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If inbred lines are used for hybrid seed production, then uniformity and reproducibility of hybrid seed are improved, but plant vigor and seed yield are reduced

Engineering Contradiction:
Improveuniformity of inbred linesVSAvoidseed yield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent segments the breeding process into distinct phases: maintaining inbred lines for uniformity, crossing them to produce F1 hybrids for vigor, and using the F1 hybrids for grain production. This segmentation allows each phase to optimize for its specific goal without compromise.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent dynamically transitions between different genetic states: homozygous inbreds for uniformity, heterozygous F1 hybrids for vigor and yield, and F2 segregating populations for further breeding. This dynamic approach allows the system to exploit the advantages of each genetic state at the appropriate stage.

Inventive Principle:
Principle #15Dynamics

2Adaptability or versatility

If multiple desirable traits are combined in a single variety, then adaptability and resilience are improved, but breeding complexity and time are increased

Engineering Contradiction:
Improveadaptability to environmental conditionsVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent creates inbred lines that serve multiple functions: they maintain genetic uniformity, provide disease resistance, contribute to hybrid vigor, and enable reproducible hybrid seed production. This multi-functionality reduces the need for separate breeding programs for each trait.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent performs preliminary selection and stabilization of desirable traits within inbred lines before crossing. This preliminary action ensures that when hybrids are produced, they already carry pre-selected traits for disease resistance and environmental adaptability, reducing the complexity of subsequent breeding steps.

Inventive Principle:
Principle #10Preliminary action

3Manufacturing precision

If transgenes are introduced to add specific traits, then trait precision and effectiveness are improved, but regulatory scrutiny and public acceptance are increased

Engineering Contradiction:
Improvetrait introduction precisionVSAvoidregulatory and public concerns
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent uses conventional breeding methods as an intermediary approach between traditional selection and genetic engineering. By using controlled crosses and selection in F1 and F2 generations, it achieves precise trait combination without directly introducing transgenes, thereby avoiding associated regulatory and public concerns.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent copies desirable traits through natural recombination and selection processes rather than direct genetic engineering. By selecting and propagating plants with desired traits through conventional breeding, it achieves the same outcome as transgene introduction but through naturally occurring genetic mechanisms.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS20250134052A1Variety corn line BDDC4624
Publication Date: 2025.05.01 SYNGENTA CROP PROTECITON AG

AI summary

The present invention provides an inbred corn line designated BDDC4624, methods for producing a corn plant by crossing plants of the inbred line BDDC4624 with plants of another corn plant. The invention further encompasses all parts of inbred corn line BDDC4624, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line BDDC4624, and plants produced according to these methods.