Maize Inbred PH24FS Breeding via Doubled Haploid Technology

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process that requires precise planning and efficient resource use, aiming to combine desirable traits such as disease resistance, drought tolerance, and high yield, while maintaining stability across various conditions and environments.

Innovation Solution

The introduction of the novel maize variety PH24FS, which involves crossing with another maize plant to introduce desired traits through backcross conversion, genetic manipulation, and transformation, including cytoplasmic or nuclear factors for male sterility, and the use of regenerable tissue cultures to produce plants with specific physiological and morphological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding processes are used to develop new maize varieties, then desirable traits can be combined, but the process takes 6-12 years and is time-consuming

Engineering Contradiction:
Improvestability of maize varietyVSAvoidbreeding cycle duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using doubled haploid technology to create inbred lines in a single generation rather than requiring multiple generations of selfing. This preliminary creation of homozygous lines accelerates the breeding process while maintaining the stability and reliability of the final variety, reducing the overall breeding cycle from 6-12 years to a much shorter duration.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces traditional mechanical breeding methods (repeated manual crossing and selection over multiple generations) with biotechnological methods including doubled haploid technology, molecular markers, and genomic selection. This substitution dramatically reduces the time required to develop stable, high-yielding maize varieties while maintaining breeding reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If multiple breeding steps are performed to combine desirable traits, then yield and resistance improve, but the process complexity increases

Engineering Contradiction:
Improvemaize yieldVSAvoidbreeding process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies universality by developing a comprehensive breeding system that integrates multiple functions into a unified approach. The system combines doubled haploid technology, molecular marker assistance, genomic selection, and traditional phenotypic evaluation into a single integrated breeding platform. This multi-functional system efficiently combines desirable traits for high yield, disease resistance, and stress tolerance while managing process complexity through standardized protocols.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent implements feedback mechanisms through molecular marker-assisted selection and genomic evaluation that continuously monitor and adjust the breeding process. These feedback systems allow real-time assessment of trait progression and enable dynamic modification of breeding strategies, thereby achieving high productivity (yield and resistance) while controlling the complexity of the breeding process through data-driven decision making.

Inventive Principle:
Principle #23Feedback

3Stability of the object's composition

If inbred lines are developed through traditional selfing, then homozygosity is achieved, but many generations are required

Engineering Contradiction:
Improvehomozygosity of inbred lineVSAvoidnumber of generations
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent replaces the traditional mechanical process of repeated selfing and selection with doubled haploid technology. This biotechnological method creates completely homozygous inbred lines in a single generation by doubling the haploid genome, eliminating the need for multiple generations of selfing. This substitution maintains the stability and homozygosity required for reliable variety development while dramatically reducing the time and generational steps involved.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS9743614B1Maize inbred PH24FS
Publication Date: 2017.08.29 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH24FS and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH24FS with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH24FS through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH24FS or a locus conversion of PH24FS with another maize variety.