Maize Inbred PH41V8 Breeding via Marker-Assisted Selection

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, typically taking six to twelve years, and existing technologies face challenges in combining desirable traits such as disease resistance, drought tolerance, and high yield in a stable and agronomically sound manner.

Innovation Solution

The introduction of the novel maize variety PH41V8, which involves genetic manipulation and transformation to incorporate traits like male sterility, herbicide tolerance, and disease resistance, along with specific breeding processes to produce hybrid maize seeds with enhanced characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding processes are used to develop new maize varieties, then desirable traits such as disease resistance and high yield can be combined, but the development process takes six to twelve years

Engineering Contradiction:
Improvestability of desirable traitsVSAvoidbreeding development time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by creating and maintaining a pre-characterized inbred maize line (PH41V8) with a comprehensive set of desirable traits including disease resistance, drought tolerance, and high yield potential. This pre-developed genetic foundation with established molecular markers allows breeders to start hybrid development immediately rather than spending years developing each parental line from scratch, thereby reducing the overall breeding cycle time while maintaining trait stability

Inventive Principle:
Principle #10Preliminary action

2Reliability

If multiple desirable traits are combined in a single maize variety, then the variety becomes more agronomically sound and stable, but the breeding process becomes more complex

Engineering Contradiction:
Improveagronomic stabilityVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the complex multi-trait breeding process into manageable components: (1) developing a pre-characterized inbred line with specific traits, (2) identifying molecular markers associated with those traits, and (3) using marker-assisted selection to track and combine traits during hybrid development. This segmentation of the breeding process into discrete, trackable steps reduces overall complexity while ensuring stable trait combination

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements feedback through marker-assisted selection, where molecular markers provide continuous information about the presence and combination of desirable traits during the breeding process. This feedback mechanism allows breeders to make informed decisions at each generation, selecting plants that are progressing toward the desired multi-trait combination, thereby simplifying the management of complex breeding programs

Inventive Principle:
Principle #23Feedback

3Adaptability or versatility

If conventional breeding methods are used, then trait combination is achieved through natural recombination, but the process requires extensive field testing and selection over multiple generations

Engineering Contradiction:
Improvetrait combination capabilityVSAvoidbreeding efficiency
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The patent applies mechanics substitution by replacing the traditional mechanical/phenotypic selection process with molecular marker-based selection. Instead of relying on visual inspection and field testing to identify plants with desired traits, the patent uses DNA markers to directly detect the presence of trait-associated genes. This substitution dramatically increases breeding efficiency by allowing early-generation selection without extensive field testing, while maintaining the ability to combine multiple traits through controlled crossing

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS10154640B1Maize inbred PH41V8
Publication Date: 2018.12.18 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH41V8 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH41V8 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH41V8 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH41V8 or a locus conversion of PH41V8 with another maize variety.