Maize Inbred PH41VG Breeding via Marker-Assisted Selection

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, taking six to twelve years, and existing technologies face challenges in creating stable, high-yielding maize varieties with desirable traits such as disease resistance, drought tolerance, and improved agronomic characteristics.

Innovation Solution

The introduction of the novel maize variety PH41VG, which involves crossing with other maize plants to introduce traits like male sterility, disease resistance, and improved agronomic characteristics through backcross conversion, genetic manipulation, and transformation, along with specific breeding processes to enhance yield and adaptability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional maize breeding processes are used to develop new varieties with desirable traits, then genetic stability and uniformity are maintained, but the development time increases significantly (6-12 years)

Engineering Contradiction:
Improvegenetic stabilityVSAvoiddevelopment time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent employs preliminary action by pre-selecting and characterizing inbred lines with specific desirable traits (disease resistance, yield potential, adaptability) before crossing. This advance preparation of parental material with known genetic characteristics accelerates the breeding process while maintaining genetic stability, as the parent lines are already optimized for the target traits.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses molecular markers to copy and track specific genetic loci through generations during backcrossing. This molecular copying approach allows precise monitoring of trait inheritance without requiring lengthy phenotypic evaluation periods, thereby reducing development time while ensuring genetic stability through marker-assisted selection.

Inventive Principle:
Principle #26Copying

2Productivity

If backcross conversion and genetic manipulation techniques are applied to introduce new traits, then desirable traits (disease resistance, yield, adaptability) are improved, but process complexity increases

Engineering Contradiction:
ImproveyieldVSAvoidbreeding process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces traditional mechanical/phenotypic selection methods with molecular marker-based selection systems. Instead of visually assessing and manually selecting plants with desired traits over multiple generations, molecular markers detect the presence of target genes at the DNA level, dramatically simplifying the selection process while enabling precise introduction of disease resistance, yield, and adaptability traits through backcrossing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces molecular markers as intermediaries between the breeder and the target traits. These markers serve as reliable indicators that mediate the selection process, allowing breeders to indirectly select for complex traits (disease resistance, yield, adaptability) through easily detectable marker signals, thereby reducing the complexity of directly evaluating and selecting for these complex phenotypic traits.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If multiple breeding steps and trait introductions are performed, then agronomic characteristics and quality are improved, but the number of years required increases

Engineering Contradiction:
Improveagronomic adaptabilityVSAvoidbreeding program duration
Core Design Contradiction:
Adaptability or versatilityVSDuration of action of stationary object

Solution Approach 1:

The patent implements continuous useful action by conducting parallel breeding operations simultaneously rather than sequentially. Multiple backcrossing generations and trait introductions occur in overlapping timeframes using controlled environments and tissue culture techniques, allowing the breeding program to maintain continuous productive activity throughout the development period, thereby reducing the overall duration while improving agronomic adaptability.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent adds temporal and spatial dimensions to the breeding process by utilizing controlled environment chambers and tissue culture systems. This allows breeding operations to proceed concurrently in different environmental conditions and spatial locations, effectively compressing the time required to achieve multiple generations of selection and trait stabilization, thus reducing breeding program duration while enhancing agronomic versatility.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS10206360B1Maize inbred PH41VG
Publication Date: 2019.02.19 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH41VG and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH41VG with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH41VG through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH41VG or a locus conversion of PH41VG with another maize variety.