Maize Inbred PH42B6 Breeding via Backcross Conversion

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, taking six to twelve years, and existing technologies face challenges in combining desirable traits such as disease resistance, drought tolerance, and high yield in a stable and agronomically sound manner.

Innovation Solution

The introduction of the novel maize variety PH42B6, which involves crossing with other maize plants to introduce desirable traits through backcross conversion, genetic manipulation, and transformation, including cytoplasmic male sterility and locus conversions, to produce stable, high-yielding hybrids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional maize breeding methods are used to combine desirable traits, then the resulting hybrids are stable and agronomically sound, but the development process takes six to twelve years

Engineering Contradiction:
Improvestability of hybridVSAvoiddevelopment time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-establishing a recurrent parent inbred line with a comprehensive base of desirable traits (disease resistance, drought tolerance, yield potential) before initiating backcrossing programs. This pre-prepared genetic foundation accelerates the breeding process while maintaining hybrid stability, as the recurrent parent is already optimized for agronomic performance before trait introgression begins

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If multiple desirable traits are combined in a single hybrid, then the hybrid becomes more agronomically sound and resistant to stresses, but the breeding process becomes more complex and time-consuming

Engineering Contradiction:
Improveresistance to diseases and stressesVSAvoidbreeding process complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges multiple desirable traits (disease resistance, drought tolerance, yield characteristics) into a single recurrent parent inbred line through cumulative backcrossing and selection. This consolidation approach simplifies subsequent breeding operations by using one pre-integrated parent rather than managing multiple separate trait introductions, thereby reducing overall program complexity while maintaining multi-trait resistance in the final hybrid

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The recurrent parent inbred line serves multiple functions simultaneously: it provides disease resistance, drought tolerance, yield potential, and acts as the genetic foundation for introgressing additional specific traits. This multi-functional design eliminates the need for separate breeding programs for each trait, reducing overall breeding complexity while achieving comprehensive agronomic performance

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If new traits are introduced through backcross conversion and genetic manipulation, then the time required for trait introduction is reduced, but the manufacturing precision of the breeding process becomes more challenging

Engineering Contradiction:
Improverate of trait introductionVSAvoidprecision of trait introgression
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent employs feedback mechanisms through molecular marker-assisted selection during backcrossing operations. Breeders use DNA markers to track the presence and absence of specific chromosomal regions, providing real-time feedback on introgression progress. This allows precise control over which parental segments are retained or eliminated, achieving high manufacturing precision in trait introgression while accelerating the breeding process through reduced phenotypic screening requirements

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS10856493B1Maize inbred PH42B6
Publication Date: 2020.12.08 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH42B6 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH42B6 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH42B6 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH42B6 or a locus conversion of PH42B6 with another maize variety.