Maize Inbred PH42M1 Breeding Acceleration via Molecular Markers

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Solution Overview

Problem

The development of new maize varieties is a time-consuming process that takes six to twelve years, and there is a continuous need for stable, high-yielding maize varieties with improved traits such as disease resistance, drought tolerance, and better agronomic characteristics.

Innovation Solution

A novel maize variety, PH42M1, is developed through careful breeding and selection, incorporating traits like male sterility, disease resistance, and improved agronomic characteristics, using techniques such as backcross conversion and genetic transformation, and processes for producing hybrid maize seeds by crossing PH42M1 with other maize varieties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional maize breeding processes are used to develop new varieties with improved traits, then disease resistance and yield improvement are achieved, but the development time becomes excessively long (6-12 years)

Engineering Contradiction:
Improvedisease resistanceVSAvoidbreeding development time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-establishing a comprehensive germplasm collection with diverse genetic backgrounds before breeding begins. This preparatory step includes gathering maize varieties with known disease resistance traits and organizing them into a structured breeding pool, thereby reducing the time required for variety selection and initial crosses in subsequent breeding programs.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses molecular markers as intermediaries to accelerate trait identification and selection. By employing DNA markers linked to disease resistance genes, breeders can screen and select desirable traits at the seedling stage rather than waiting for field performance evaluation, dramatically shortening the breeding cycle while maintaining reliability of trait inheritance.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If multiple desirable traits are combined in a single maize variety through breeding, then agronomic performance and yield are improved, but the breeding process complexity increases significantly

Engineering Contradiction:
ImproveyieldVSAvoidbreeding process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the complex breeding process into distinct modular stages: germplasm collection, preliminary crossing, backcrossing for trait introgression, selfing for homozygosity, and multi-environment testing. Each stage has specific objectives and selection criteria, allowing systematic accumulation of desirable traits while managing complexity through structured progression rather than simultaneous manipulation of multiple traits.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs universal breeding protocols that can be applied across different maize varieties and trait combinations. The standardized backcrossing scheme and selection procedures serve multiple functions: they can introgress different disease resistance genes, adapt varieties to various environments, and maintain yield performance, thereby reducing the need for variety-specific breeding approaches and simplifying the overall process.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If stable, high-yielding maize varieties are developed through extensive breeding, then agronomic soundness and yield stability across environments are achieved, but the time from first cross to seed delivery becomes excessively long

Engineering Contradiction:
Improveyield stabilityVSAvoidtime from first cross to seed delivery
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent implements feedback mechanisms through multi-environment trials and performance monitoring at various breeding stages. Data from field tests on disease resistance, yield, and adaptability are fed back into the selection process, allowing rapid identification of superior genotypes that perform consistently across environments. This feedback loop enables early elimination of unstable lines and acceleration of stable variety development.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent utilizes parameter changes by evaluating maize lines under varying environmental conditions (different locations, years, disease pressures) to assess yield stability. By changing environmental parameters systematically and analyzing performance responses, the breeding program identifies genotypes with stable yield across conditions, reducing the need for prolonged testing while ensuring agronomic soundness.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS10653083B1Maize inbred PH42M1
Publication Date: 2020.05.19 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH42M1 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH42M1 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH42M1 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH42M1 or a locus conversion of PH42M1 with another maize variety.