Maize Inbred PH4DB2 Breeding Acceleration

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Solution Overview

Problem

The development of new maize varieties is a time-consuming process that takes six to twelve years, and there is a continuous goal to create stable, high-yielding maize varieties with desirable traits such as disease resistance, drought tolerance, and improved agronomic characteristics.

Innovation Solution

A novel maize variety, PH4DB2, is developed through careful breeding and selection, incorporating traits like male sterility, disease resistance, and drought tolerance, achieved through backcross conversion, genetic manipulation, and transformation, allowing for the creation of hybrid maize seeds with enhanced characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional maize breeding processes are used to develop new varieties with desirable traits, then the maize varieties achieve stable high-yielding characteristics with disease resistance and drought tolerance, but the development process takes six to twelve years which is time-consuming

Engineering Contradiction:
Improvestability of maize varietyVSAvoidbreeding development time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-selecting and characterizing inbred line PH4DB2 with specific desirable traits (disease resistance, drought tolerance, yield stability) before hybrid development. The inbred line is prepared in advance with known genetic characteristics, allowing faster hybridization and evaluation compared to traditional breeding where selection occurs throughout the entire 6-12 year process. This preliminary characterization of parent lines accelerates the overall variety development timeline while maintaining reliability.

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If multiple desirable traits are combined in a single maize variety through breeding, then the maize achieves greater yield and resistance to diseases and insects, but the breeding process becomes more complex and time-consuming

Engineering Contradiction:
Improvenumber of desirable traitsVSAvoidbreeding process complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges multiple desirable traits (disease resistance, drought tolerance, yield stability, male sterility) into a single inbred line PH4DB2 through systematic breeding. By consolidating these traits in one parent line, the patent simplifies the breeding process for developing multi-trad hybrid varieties. The inbred line serves as a unified genetic platform that combines several beneficial characteristics, reducing the complexity of managing multiple separate breeding programs for different traits.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The inbred line PH4DB2 is developed as a universal parent line that can be used across multiple hybrid combinations to impart desirable traits. The line possesses multiple functions: it provides disease resistance, drought tolerance, yield stability, and male sterility for hybrid seed production. This multi-functionality allows the same inbred line to be deployed in various breeding programs targeting different trait combinations, reducing overall breeding complexity while maintaining high adaptability.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If male sterility is introduced into maize variety for hybrid seed production, then self-pollination is prevented and hybrid vigor is enhanced, but the variety requires additional genetic manipulation and transformation steps

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic manipulation process
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The inbred line PH4DB2 possesses intrinsic male sterility, a self-service mechanism that automatically prevents self-pollination without requiring external intervention during flowering. The plant's own genetic constitution ensures that it cannot self-fertilize, thereby guaranteeing cross-pollination and hybrid seed production. This self-service approach to preventing selfing simplifies field management compared to mechanical detasseling or chemical treatments, even though the male sterile trait was introduced through genetic manipulation in the breeding process.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS11470804B1Maize inbred PH4DB2
Publication Date: 2022.10.18 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH4DB2 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH4DB2 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH4DB2 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH4DB2 or a locus conversion of PH4DB2 with another maize variety.