Maize PH4D4B Breeding via Molecular Markers

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Solution Overview

Problem

The development of new maize varieties and hybrids is a time-consuming process, taking six to twelve years, and existing technologies face challenges in combining desirable traits such as disease resistance, drought tolerance, and high yield in a single variety that is agronomically sound across different conditions and environments.

Innovation Solution

A novel maize variety, PH4D4B, is developed through careful breeding and selection, incorporating traits like male sterility, disease resistance, and drought tolerance, achieved through backcross conversion, genetic manipulation, and transformation, allowing for the creation of stable, high-yielding hybrids with improved agronomic characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop new maize varieties, then desirable traits such as disease resistance, drought tolerance, and high yield can be combined in a single variety, but the development process takes six to twelve years

Engineering Contradiction:
Improvecombination of desirable traitsVSAvoiddevelopment time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent uses molecular markers as intermediary tools to identify and track desirable traits during breeding. These markers serve as mediators that allow breeders to select plants with desired traits more efficiently, reducing the time required to develop new varieties while maintaining the ability to combine multiple traits such as disease resistance, drought tolerance, and high yield

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces traditional mechanical/visual selection methods with molecular marker-based selection. Instead of relying on phenotypic observation and manual selection processes that take multiple years, the invention uses DNA-level analysis to identify plants carrying desired traits, dramatically accelerating the breeding process while maintaining trait combination accuracy

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If multiple desirable traits are combined in a single maize variety, then the variety becomes more agronomically sound across different conditions and environments, but the breeding process becomes more complex

Engineering Contradiction:
Improveagronomic soundnessVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements feedback mechanisms through molecular marker analysis at various stages of the breeding process. By continuously monitoring the presence and combination of desirable traits using genetic markers, breeders can make informed decisions about which plants to advance, cross, or discard, thereby managing the complexity of combining multiple traits while ensuring agronomically sound varieties are developed

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS11533864B1Maize inbred PH4D4B
Publication Date: 2022.12.27 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated PH4D4B and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH4D4B with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH4D4B through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH4D4B or a locus conversion of PH4D4B with another maize variety.