Malus–Prunus Fruit Extract Composition for Atherosclerosis Prevention
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current treatments for atherosclerosis, including clinical drugs and traditional Chinese medicines, have significant side effects and a need for a more natural and safe intervention.
Innovation Solution
A composition comprising Malus niedzwetzkyana Dieck and Prunus cerasifera Ehrhart extracts, in various weight ratios and forms, is used to resist atherosclerosis, potentially offering a synergistic effect.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If clinical drugs (lipid-lowering drugs, anti-platelet drugs) are used to treat atherosclerosis, then atherosclerosis treatment effect is improved, but side effects (liver and muscle damage, gastrointestinal reactions) increase
Solution Approach 1:
The patent uses natural fruit extracts (Malus niedzwetzkyana and Prunus cerasifera) as temporary, natural interventions that can be consumed without long-term commitment to specific dosing regimens, replacing permanent medication dependency with a more flexible natural approach
Solution Approach 2:
The patent changes the chemical composition parameters by using a specific combination of fruit extracts rich in polyphenols and flavonoids, altering the treatment mechanism from synthetic drugs to natural compounds with different pharmacological profiles that reduce side effects while maintaining efficacy
2Reliability
If traditional Chinese medicines are used to treat atherosclerosis, then atherosclerosis treatment effect is improved, but side effects increase
Solution Approach 1:
The patent extracts and isolates specific active components (polyphenols, flavonoids) from the fruit materials, separating the beneficial effects from the complex traditional medicine formulations that cause side effects, thereby achieving purified therapeutic action
Solution Approach 2:
The patent creates a composite formulation combining Malus niedzwetzkyana and Prunus cerasifera extracts, leveraging the synergistic effects of multiple natural compounds together to achieve better treatment efficacy with reduced side effects compared to single-ingredient traditional medicines
3Object-affected harmful factors
If a more natural and safe way for intervention is needed, then side effects are reduced, but treatment efficacy may be compromised
Solution Approach 1:
The patent uses the fruit extracts as intermediary substances that mediate between the patient's body and the atherosclerosis pathology, providing a gentle, natural intervention that modulates the disease process without the harsh effects of direct pharmaceutical action
Solution Approach 2:
The patent changes the therapeutic parameters by utilizing the high polyphenol and flavonoid content in the fruit extracts, which have been shown to improve lipid profiles and reduce inflammation, thereby achieving both safety and efficacy through natural chemistry rather than synthetic drug mechanisms
Data Source
AI summary
A composition of Malus niedzwetzkyana Dieck and Prunus cerasifera Ehrhart, wherein the weight ratio of Malus niedzwetzkyana Dieck to Prunus cerasifera Ehrhart is 1:10-10:1. The composition has a synergistic effect in terms of preventing and-or treating atherosclerosis. The product forms of the composition of Malus niedzwetzkyana Dieck and Prunus cerasifera Ehrhart include a fruit juice, a jam, a fruit powder, oral liquid products, capsules, tablets, etc.