Mamaki Extract Composition for Cognitive Function Formulation

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Solution Overview

Problem

There is a need for improved compositions derived from Pipturis albidis (Mamaki plant) to promote cognitive functions, improve memory and recall, and prevent dementia, which are also suitable for human and animal consumption in various forms such as beverages, foods, supplements, and pet treats.

Innovation Solution

A formulation comprising a therapeutically effective amount of dried Pipturis albidis fruit extract, combined with leaf and stem extracts, optionally with excipients, in forms like pills, capsules, or beverages, designed to enhance cognitive function and prevent dementia.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a composition is derived from multiple parts of the Mamaki plant (fruit, leaf, stem), then the cognitive function promotion effect is improved, but the manufacturing complexity increases

Engineering Contradiction:
Improvecognitive function promotion effectVSAvoidmanufacturing complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines extracts from multiple parts of the Mamaki plant (fruit, leaf, and stem) into a single unified composition. This merging of multiple plant parts achieves synergistic cognitive benefits while the patent resolves the manufacturing complexity through a standardized extraction and formulation process that integrates these components systematically.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite botanical extract composition that integrates active compounds from different plant parts (fruit, leaf, stem). This composite approach enhances the therapeutic effect for cognitive function promotion by leveraging the complementary properties of each plant part while maintaining a cohesive formulation.

Inventive Principle:
Principle #40Composite materials

2Reliability

If the composition contains greater than 5% dried fruit material, then the therapeutic effectiveness is improved, but the manufacturing precision requirements increase

Engineering Contradiction:
Improvetherapeutic effectivenessVSAvoidmaterial composition precision
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent specifies a quantitative parameter threshold (greater than 5% dried fruit material) to ensure therapeutic effectiveness. This parameter-based approach allows for standardized manufacturing processes that can reliably achieve the desired composition range, balancing effectiveness requirements with manufacturability through defined specifications rather than exact precision.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20260077008A1Composition for promoting cognitive functions and methods of making and using the same
Publication Date: 2026.03.19 NAKAMURA MICHAEL

AI summary

Compositions of the present invention are conducive to the promotion of cognitive functions. Specifically, the compositions of the present invention comprise a formulation derived from the fruit, leaf, and stem of Pipturis albidis, also known as Mamaki. Specifically, the formulation comprises a therapeutically effective amount of an active composition consisting of greater than about 5% material obtained from the dried fruit of Pipturis albidis with the balance of the active composition comprising material obtained from the leaves and/or the stem thereof. Optionally, one or more excipient, or inactive ingredients, may be present.