Mangiferin and Tigernut Extract Composition for Cognitive Enhancement

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Solution Overview

Problem

Caffeine and theobromine-based energy-enhancing products cause undesirable side effects such as nervousness, anxiety, and addiction, limiting their long-term use and safety, especially for individuals like pregnant women and children.

Innovation Solution

A composition combining extracts of Tigernut (Cyperus esculentus) and mangiferin, which mimics the alertness and cognitive benefits of caffeine without the side effects, by enhancing gamma wave activity and reducing alpha wave activity in the brain, thereby providing sustained attention and memory enhancement without addiction potential.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If caffeine and theobromine are used to enhance alertness and cognitive function, then attention and concentration are improved, but nervousness, anxiety, and addiction occur

Engineering Contradiction:
Improvealertness and concentrationVSAvoidnervousness, anxiety, and addiction
Core Design Contradiction:
Ease of operationVSObject-generated harmful factors

Solution Approach 1:

The patent extracts and isolates specific compounds (mangiferin, quercetin, luteolin) from plant sources to create a composition that provides cognitive enhancement without the harmful stimulant effects of caffeine. This extraction principle allows selective acquisition of beneficial properties while eliminating adverse effects.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces plant-derived compounds as intermediary substances that mediate between the need for cognitive enhancement and the avoidance of harmful stimulants. These compounds act as alternative mediators that achieve the desired effect (improved attention and concentration) through different physiological pathways than caffeine, thereby avoiding nervousness, anxiety, and addiction.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Duration of action of moving object

If high doses of caffeine are consumed to achieve sustained energy boost, then alertness and performance are enhanced, but side effects such as arrhythmias, increased blood pressure, and insomnia increase

Engineering Contradiction:
Improvesustained energy boostVSAvoidarrhythmias, increased blood pressure, and insomnia
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters of the composition by using plant-derived compounds with different pharmacological profiles than caffeine. These compounds provide sustained energy release through gradual metabolism and different mechanisms of action, avoiding the sharp peaks and crashes associated with high-dose caffeine consumption.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite composition containing multiple plant-derived compounds (mangiferin, quercetin, luteolin) that work synergistically to provide sustained cognitive enhancement. This composite approach distributes the functional load across multiple substances, preventing the overstimulation and harmful effects associated with high doses of single stimulants like caffeine.

Inventive Principle:
Principle #40Composite materials

3Productivity

If caffeine is used to improve sports performance and reaction time, then endurance and intensity are increased, but coordination and sleep quality deteriorate

Engineering Contradiction:
Improvesports performance and reaction timeVSAvoidcoordination and sleep quality
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent employs plant-derived compounds that are naturally metabolized and eliminated from the body without accumulation, providing short-term performance enhancement without long-term negative effects on coordination and sleep. These compounds offer a temporary boost similar to caffeine but with cleaner metabolic profiles that do not disrupt sleep architecture or motor coordination.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentUS11376294B2Mangiferin-containing compositions for improving sports performance
Publication Date: 2022.07.05 NEKTIUM PHARMA SL
  • US11376294B2 patent drawing
  • US11376294B2 patent drawing
  • US11376294B2 patent drawing

AI summary

A method for enhancing at least one of alertness, attention, concentration and memory in a person in need thereof, comprising co-administering an effective amount of mangiferin, norathyriol, or an extract comprising mangiferin or norathyriol; and caffeine to the person. The components may be co-administered in a single composition, or administered in separate compositions. The mangiferin and/or norathyriol exhibit synergistic effects on brain wave activity when co-administered with caffeine.