Mannose Oligosaccharide Composition via Microreactor Polycondensation
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Solution Overview
Problem
Current mannose oligosaccharide compositions used in animal feed are not highly pure, have inconsistent effects, are not soluble in water, and have a significant environmental impact due to waste streams, limiting their practicality and effectiveness in improving gut health and reducing bacterial contamination in animals.
Innovation Solution
A water-soluble mannose oligosaccharide composition is produced through polycondensing mannose in a microreactor with an acidifying catalyst, followed by optional neutralization and refinement, resulting in a product with high solubility and improved stability, which can be effectively used in animal feed and human applications.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If mannose oligosaccharide is extracted from yeast cell walls or natural sources, then the composition is obtained, but it is not highly pure, has inconsistent composition, and is not soluble in water
Solution Approach 1:
The patent changes the physical and chemical parameters of the mannose oligosaccharide by controlling the degree of polymerization (DP2: DP3+ ratio) and molecular weight distribution through enzymatic hydrolysis conditions. This produces a water-soluble composition with consistent purity, eliminating the need for extraction from yeast cell walls while achieving both high manufacturing precision and water solubility.
Solution Approach 2:
The patent extracts only the beneficial mannose oligosaccharide components from mannans through controlled enzymatic hydrolysis, separating them from the complex yeast cell wall matrix. This selective extraction achieves high purity and water solubility while maintaining the biological activity of the mannose oligosaccharides.
2Reliability
If mannose oligosaccharide compositions are used in animal feed, then gut health and bacterial contamination are addressed, but the environmental impact is significant due to waste streams
Solution Approach 1:
The patent converts the potentially harmful waste streams from traditional extraction processes into beneficial byproducts. The enzymatic hydrolysis process generates soluble sugars and other components that can be utilized in animal feed, eliminating waste disposal issues while maintaining the effectiveness of bacterial contamination reduction.
3Adaptability or versatility
If existing mannose oligosaccharide compositions are applied in liquid feed and drinking water, then the application is attempted, but the lack of water solubility makes it impractical
Solution Approach 1:
The patent modifies the molecular parameters of the mannose oligosaccharide by controlling the degree of polymerization and molecular weight distribution. This produces a water-soluble composition that can be effectively applied in liquid feed and drinking water, achieving both adaptability and ease of operation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition enhances growth performance, digestive health, immune system modulation, and reduces bacterial loads in animals, offering improved solubility and reduced environmental impact compared to existing products.
Implementation Method 1
Polycondensing mannose by passing the mannose through a microreactor at a temperature of from 180° C. to 240° C. in the presence of an acidifying catalyst to produce a manno-oligosaccharide containing composition
Implementation Method 2
Polycondensing mannose by passing the mannose through a microreactor at a temperature of from 180° C. to 240° C.
Data Source
AI summary
The present invention relates to a composition comprising mannose oligosaccharide and a process for making such. The present invention further relates to a composition comprising mannose oligosaccharide for use in the treatment of a human or animal.