Nutriprotective Diet Using Maple Syrup Polyphenols for Liver Protection

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Solution Overview

Problem

Current diets lack effective natural components to prevent and treat liver diseases, with maple syrup being a popular yet understudied natural sweetener that may offer hepatoprotective benefits.

Innovation Solution

A nutriprotective diet comprising a nutriprotective amount of sugar plant syrup, sugar plant syrup extract, or combinations thereof, including maple syrup, which provides a hepatoprotective effect by down-regulating cellular amino acid metabolism and liver enzyme production, and a method for extracting polyphenolic compounds from maple syrup using adsorbent materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If maple syrup is used as a natural sweetener in diet, then hepatoprotective effect is improved, but scientific evidence was previously unavailable

Engineering Contradiction:
Improvehepatoprotective effectVSAvoidscientific evidence
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The patent uses polyphenolic compounds as intermediaries to transfer the hepatoprotective effect from maple syrup to the liver. These compounds act as mediators that carry the protective function, allowing the effect to be isolated, studied, and scientifically validated without requiring direct administration of large amounts of maple syrup.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent extracts polyphenolic compounds from maple syrup to create a concentrated extract. This extraction process separates the active hepatoprotective components from the bulk syrup, enabling scientific study of the specific compounds responsible for the protective effect and providing measurable evidence of mechanism of action.

Inventive Principle:
Principle #2Taking out (Extraction)

2Reliability

If natural products like maple syrup are increased in diet, then prevention of liver diseases is improved, but diagnostic and therapeutic methods are still lacking

Engineering Contradiction:
Improveprevention of liver diseasesVSAvoiddiagnostic and therapeutic methods
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent segments the complex problem of liver disease prevention into identifiable components: specific polyphenolic compounds from maple syrup, their mechanisms of action on cellular amino acid metabolism and liver enzyme production, and measurable biomarkers. This segmentation enables development of diagnostic and therapeutic methods based on understanding individual compound effects.

Inventive Principle:
Principle #1Segmentation

3Reliability

If maple syrup extract is used to treat liver diseases, then treatment effectiveness is improved, but current therapeutic agents are ineffective

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidineffective therapeutic agents
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical parameters of therapeutic intervention by using polyphenolic compounds with specific molecular structures and concentrations. These parameter changes in compound identity, concentration, and purity enable effective treatment where previous agents failed, by targeting specific cellular pathways involved in liver disease.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The diet and extracted compounds demonstrate hepatoprotective effects by reducing liver impairment markers and modulating gene expression, potentially preventing and treating liver diseases, metabolic syndrome, and other disorders.

Implementation Method 1

a process for the extraction of polyphenolic compounds from maple syrup using adsorbent materials

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS11826396B2Nutriprotective diet
Publication Date: 2023.11.28 FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC
  • US11826396B2 patent drawing
  • US11826396B2 patent drawing
  • US11826396B2 patent drawing

AI summary

The present document describes a nutriprotective diet comprising a nutriprotective amount of a sugar plant syrup, a sugar plant syrup extract, a sugar plant extract, or combinations thereof. The present document also describes a method of eliciting a nutriprotective effect in a subject, which comprises administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document also describes a method of treating a subject with a disorder, by administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document describes a process for the extraction of polyphenolic compounds from maple syrup using adsorbent materials, and the extracts obtained therefrom.