Mass Spectrometer Charge-Up Detection via Ion Intensity Signals

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Solution Overview

Problem

Mass spectrometers face inefficiencies in maintenance due to the need for operators to rely on experience to identify and address ion optical element contamination, leading to time-consuming and cumbersome processes for diagnosing and resolving charge-up issues.

Innovation Solution

A mass spectrometer equipped with a device state determiner, charge-up determiner, and notifier that performs automated analysis to identify abnormal states and locate charge-up in ion optical elements by changing voltages applied to these elements, allowing for efficient identification and notification of contaminated components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated charge-up detection is implemented, then maintenance efficiency is improved, but device complexity increases

Engineering Contradiction:
Improvemaintenance efficiencyVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The mass spectrometer performs self-diagnosis by automatically detecting charge-up conditions in ion optical elements through monitoring ion intensity signals, eliminating the need for operator experience and manual inspection. The system identifies contaminated elements and notifies users automatically, enabling maintenance personnel to directly clean identified components without time-consuming diagnostic processes.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system continuously monitors ion intensity signals from the ion detector and compares them against reference values to detect deviations indicating charge-up conditions. This feedback mechanism enables real-time identification of contaminated ion optical elements, allowing the system to automatically determine which components require maintenance based on actual performance data.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If manual inspection by experienced operators is used, then diagnostic accuracy is improved, but loss of time increases

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidtime for identifying contaminated elements
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system replaces manual visual inspection and experience-based judgment with automated electronic monitoring of ion intensity signals. The control unit processes electrical signals from the ion detector to objectively identify charge-up conditions, eliminating subjectivity and variability associated with human operators while significantly reducing diagnostic time.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The ion intensity signal serves as an intermediary parameter that objectively reflects the charge-up state of ion optical elements. By monitoring this measurable physical quantity, the system translates the abstract concept of contamination into quantifiable data that can be automatically analyzed and compared against reference values for accurate identification.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If comprehensive checking of all ion optical elements is performed, then reliability is improved, but loss of time increases

Engineering Contradiction:
Improvedetection reliabilityVSAvoidchecking time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system extracts and identifies only the specific ion optical elements exhibiting charge-up conditions from the complete set of elements, rather than requiring comprehensive inspection of all components. By isolating and notifying users about only the contaminated elements based on ion intensity signal analysis, the system enables targeted maintenance that maintains reliability while minimizing time loss.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables operators with varying skill levels to quickly identify and address ion optical element contamination, improving maintenance efficiency by automating the charge-up detection process and preventing unnecessary checks when the device is in a normal state.

Implementation Method 1

a plurality of ion optical elements each of which is used for transporting ions or controlling the behavior of ions by an effect of an electric field

Methodology Applied
Scientific EffectElectric field: Electric Field

Implementation Method 2

determining whether or not charge-up is likely to be present in the plurality of ion optical elements and locating the charge-up if charge-up is likely to be present, based on a change in the ion intensity signal observed in the analysis performed on the predetermined sample while one or more of voltages applied to the plurality of ion optical elements are changed

Methodology Applied
Scientific EffectIon intensity signal:

Data Source

PatentUS11990326B2Mass spectrometer with charge up determiner using ion intensity signal
Publication Date: 2024.05.21 SHIMADZU CORP
  • US11990326B2 patent drawing
  • US11990326B2 patent drawing
  • US11990326B2 patent drawing

AI summary

In a mass spectrometer including ion optical elements for transporting ions or controlling their behavior by electric fields, a device state determiner (41, 52) determines whether or not the mass spectrometer is in a normal state based on an ion intensity signal acquired by analyzing a predetermined sample. If the mass spectrometer is in an abnormal state, a charge-up determiner (42, 53) determines whether or not charge-up is present in the ion optical elements based on a change in ion intensity signal in an analysis on the predetermined sample observed when the voltages applied to the ion optical elements are changed according to a predetermined sequence. If charge-up is present, the charge-up determiner determines which ion optical element is likely to have the charge-up. A notifier (8, 61) notifies a user of the results of the determination by the device state determiner and the charge-up determiner.