Measuring Device Abnormality Detection via Transmitted Light

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Solution Overview

Problem

Conventional methods for detecting measurement abnormalities, such as the presence of bubbles or foreign bodies, in measurement systems are cumbersome and increase hardware and software development burdens, and require continuous monitoring during reactions, making it difficult to detect abnormalities efficiently without increasing the load on the apparatus.

Innovation Solution

A measuring device and method that involves emitting light to a measurement target region, moving the position of the target or light source, and comparing light measurement values over multiple positions to determine abnormality, where a reference measurement value is compared to subsequent highest values to detect anomalies, allowing for easy detection of measurement abnormalities without increasing hardware load.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If scattered light method is used to detect measurement abnormality, then measurement sensitivity is improved, but device complexity and foreign body reaction susceptibility increase

Engineering Contradiction:
Improvemeasurement sensitivityVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces the mechanical/optical scattered light detection system with a simpler transmitted light measurement system. Instead of using multiple light receivers at different angles to detect scattered light, the invention uses a single transmitted light measurement combined with temporal comparison to detect measurement abnormalities, thereby reducing device complexity while maintaining detection capability

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces time as an intermediary parameter to detect measurement abnormalities. By comparing transmitted light measurement results across different time points, the system can identify abnormalities without needing complex optical scattering detection hardware, thus reducing device complexity while preserving measurement precision

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If foreign body detector with camera is used to observe channel, then measurement abnormality detection capability is improved, but hardware load and software development burden increase

Engineering Contradiction:
Improvemeasurement abnormality detection capabilityVSAvoidhardware load
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential function of foreign body detection from the complex camera-based system by using only transmitted light measurement. Instead of implementing a full camera system with image processing software, the invention extracts the core detection capability through simple light transmission measurement and temporal comparison, thereby reducing hardware load while maintaining abnormality detection capability

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces expensive, complex camera-based foreign body detection with a simpler, more economical transmitted light measurement system. The invention uses basic optical components and software-based temporal comparison instead of costly camera hardware and complex image analysis software, achieving the same detection function with reduced hardware load

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Measurement precision

If continuous monitoring is performed during reaction to detect foreign body, then measurement abnormality detection accuracy is improved, but productivity decreases due to increased monitoring load

Engineering Contradiction:
Improvemeasurement abnormality detection accuracyVSAvoidproductivity
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent implements periodic monitoring at specific time points during the reaction process rather than continuous monitoring. By measuring transmitted light at the start and at subsequent intervals, the system achieves adequate abnormality detection accuracy while minimizing the monitoring load, thus maintaining productivity

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent applies partial monitoring by selecting specific critical time points for measurement rather than continuous monitoring throughout the entire reaction. This partial action approach provides sufficient abnormality detection capability while reducing the overall monitoring burden, thereby preserving productivity

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient detection of measurement abnormalities during reactions, reducing hardware load and allowing for accurate determination of measurement issues caused by bubbles or foreign bodies, even during ongoing reactions, by using a program that compares light measurement values across different positions to identify deviations.

Implementation Method 1

an emission means that emits light to a measurement target region; a light measurement means that measures light output from the measurement target region by emission with the emission means

Methodology Applied
Scientific EffectLight emission and detection: Light

Data Source

PatentUS11397150B2Measuring device, measurement abnormality detecting method, and program
Publication Date: 2022.07.26 OTSUKA PHARM CO LTD
  • US11397150B2 patent drawing
  • US11397150B2 patent drawing
  • US11397150B2 patent drawing

AI summary

Presently disclosed is a way to provide a measuring device capable of easily detecting measurement abnormality without increasing load in hardware. The measuring device may include: an emission means that may emit light to a measurement target region; a light measurement means that may measure light output from the measurement target region by emission with the emission means; a driving means that may move a position of at least one of the measurement target region and the emission means; and a determination means that may compare measurement values of the light measured a plurality of times by the light measurement means while changing positions of the measurement target region by the driving means and thereby determines abnormality of a measurement result. The determination means may determine measurement abnormality in a case where a reference measurement value being a measurement value obtained for a first time is lower than a comparison measurement value being a highest measurement value among measurement values obtained for second and subsequent times.