Medical Delivery Device Threaded Rod Actuation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current medical delivery devices are complex and cumbersome for precise dosing and self-administration of liquids, particularly for small volumes, and often require trained personnel, limiting their use for patient self-administration.

Innovation Solution

A medical delivery device featuring a rod element with a stem and a dosage member, where the stem extends into the dosage member's chamber body, allowing for precise dosing through a thread arrangement, enabling easy rotation and axial movement, and a switching mechanism to separate dosing and delivery statuses, facilitating convenient self-administration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If syringes are used to deliver liquid pharmaceutical substances, then precise dosing can be achieved, but the device becomes complex and requires trained personnel for operation

Engineering Contradiction:
Improvedosing precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The device is divided into distinct functional modules: a cartridge containing the pharmaceutical substance, a hub assembly with a needle, and a actuator mechanism. This segmentation allows each component to be optimized independently while simplifying the overall operation for the patient.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The needle is nested within a protective sheath that is integrated into the hub assembly. The cartridge is inserted into the hub, creating a compact nested structure that reduces complexity and prevents accidental needle exposure during storage and transport.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Measurement precision

If syringes are used for liquid delivery, then precise dosing is possible, but self-administration becomes challenging for patients

Engineering Contradiction:
Improvedosing precisionVSAvoidease of self-administration
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The device is designed as a self-contained system where the patient can independently prepare and administer the medication. The cartridge pre-contains the precise dose, and the actuator mechanism is designed to be operated with simple finger movements, eliminating the need for training in complex syringe techniques.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The pharmaceutical substance is pre-loaded into the cartridge at the manufacturing stage with precise dosing already configured. This preliminary action removes the need for the patient to perform complex dosing calculations or manual filling operations.

Inventive Principle:
Principle #10Preliminary action

3Ease of operation

If prefilled syringes are used, then self-administration is enabled, but manufacturing becomes complicated and expensive

Engineering Contradiction:
Improveself-administration capabilityVSAvoidmanufacturing complexity
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

The device separates the pharmaceutical substance containment (cartridge) from the delivery mechanism (hub and needle assembly). This allows the cartridge to be manufactured using standard vial or pre-filled syringe techniques, while the hub assembly can be produced separately and assembled, simplifying the overall manufacturing process.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The hub assembly is designed to accept different cartridge types and configurations, allowing a single hub design to serve multiple dosing requirements and pharmaceutical substances, thereby reducing manufacturing complexity and tooling costs.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Ease of operation

If injection pens are used for diabetes therapy, then self-administration is facilitated, but the devices remain relatively complex

Engineering Contradiction:
Improveself-administration easeVSAvoiddevice complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The needle is extracted as a separate, replaceable component that can be attached to the hub assembly only when needed. This eliminates the need for complex needle retraction mechanisms or integrated needle-cartridge designs, simplifying the overall device structure while maintaining ease of use.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The device incorporates a dynamic actuator mechanism that transitions from a loading position to an injection position through simple user manipulation. This dynamic design allows the device to adapt to different injection sites and patient needs without requiring multiple complex components.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device allows for precise dosing and convenient self-administration of liquids, reducing the need for trained personnel and simplifying the process, while ensuring accurate and safe delivery of medications.

Implementation Method 1

the rod element is movable along its longitudinal axis relative to the delivery orifice of the dosage member by the first thread arrangement of the stem of the rod element and a second thread arrangement travelling along each other

Methodology Applied
Scientific EffectThread mechanism: Screw

Data Source

PatentEP3389593B1Medical delivery device
Publication Date: 2024.04.24 F HOFFMANN LA ROCHE & CO AG
  • EP3389593B1 patent drawingFigure 1
  • EP3389593B1 patent drawingFigure 2~3
  • EP3389593B1 patent drawingFigure 4~5

AI summary

Medical delivery device (10) comprises a rod element (30) and a dosage member (60). The rod element (30) has a stem (310) with a longitudinal axis (380), a first thread arrangement (3320, 3330), a distal end and a proximal end. The dosage member (60) comprises a delivery orifice (620) and a chamber body (610) with a distal end, a proximal end and a hollow interior. The stem (310) of the rod element (30) extends into the interior of the chamber body (610) of the dosage member (60) and the delivery orifice (620) is arranged adjacent to the proximal end of the stem (310) of the rod element (30). In a dosing status of the medical delivery device (10), the rod element (30) is movable along its longitudinal axis (380) relative to the delivery orifice (620) of the dosage member (60) by the first thread arrangement (3320, 3330) of the stem (310) of the rod element (30) and a second thread arrangement (650) travelling along each other. Thereby, a dosage chamber (6110) is formed in the interior of the chamber body (610) of the dosage member (60) between the stem (310) of the rod element (30) and the delivery orifice (620) which dosage chamber (6110) increases when the rod element (30) moves away from the delivery orifice (620). The dosage member (60) comprises the second thread arrangement (650). Thereby, in the dosing status of the medical delivery device (10), the first thread arrangement (3320, 3330) of the rod element (30) engages the second thread arrangement (650) of the dosage member (60).