Medical Dressing with Cellulose Nanocellulose Composite for Stable Oil Release

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Solution Overview

Problem

Current medical dressings face challenges with stability and convenience, as they often require complex application and have a short shelf-life due to the instability of active compositions, which can oxidize and lose functionality over time, especially when exposed to air.

Innovation Solution

A medical dressing with a composite material comprising oil droplets dispersed in a matrix of cellulose derivatives and nanocellulose, which remains dry and solid until applied, allowing for easy application, reducing microbial growth, and providing a controlled release of antimicrobial oils to prevent infections and promote wound healing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If active compositions are pre-prepared in medical dressings, then the dressing provides immediate therapeutic effect, but the active compositions oxidize and lose functionality over time

Engineering Contradiction:
Improvetherapeutic effectVSAvoidshelf-life
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The medical dressing incorporates oil-containing composite material in advance, but the oil remains encapsulated in a solid matrix structure until the dressing is applied to the wound. The oil is pre-positioned within the dressing structure, ready for controlled release upon contact with wound exudate or application pressure, rather than being released immediately upon manufacturing

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The dressing utilizes a phase change mechanism where the oil-containing composite material transitions from a solid encapsulated state during storage and application to a liquid released state when exposed to wound conditions. This parameter change allows the oil to remain stable and non-leaking during storage, then become fluid and therapeutic when needed at the wound site

Inventive Principle:
Principle #35Parameter changes

2Reliability

If oil composition is incorporated into medical dressing, then pressure ulcer prevention and microbial functionality are improved, but the dressing becomes messy and difficult to apply

Engineering Contradiction:
Improvepressure ulcer preventionVSAvoidapplication convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The oil-containing composite material is encapsulated within a solid matrix structure that acts as a flexible shell, containing the oil in a non-messy form during handling and application. The solid matrix provides a thin film structure that can be easily applied to the wound area without the oil leaking or smearing during the application process

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The dressing exploits a phase change from solid to liquid state. During storage and application, the oil is in a solid encapsulated state within the composite material matrix, making the dressing easy to handle and apply without mess. Upon contact with wound exudate or application pressure, the oil transitions to a liquid state for effective release and therapeutic action

Inventive Principle:
Principle #35Parameter changes

3Reliability

If oil is released continuously from medical dressing, then therapeutic effect is maintained, but the shelf-life is shortened due to oxidation

Engineering Contradiction:
Improvetherapeutic effectVSAvoidshelf-life
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The oil is pre-positioned and encapsulated within the solid matrix structure of the composite material during manufacturing, but remains dormant and non-releasing during storage. The therapeutic release is triggered only after the dressing is applied to the wound, ensuring the oil remains protected from oxidation during the entire shelf-life period

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The dressing utilizes a controlled phase change mechanism where the oil remains in a stable solid encapsulated state during storage, preventing oxidation and extending shelf-life. Upon application to the wound, changes in temperature, pressure, or contact with wound exudate trigger the oil to transition to a liquid state and release therapeutically

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The dressing maintains a long shelf-life, is easy to apply, and effectively prevents infections and pressure ulcers by releasing antimicrobial agents upon pressure, ensuring improved wound healing and extended functionality.

Implementation Method 1

the medical dressing comprises a composite material comprising oil droplets dispersed in a matrix

Methodology Applied
Scientific EffectEncapsulation:

Implementation Method 2

The pressure exerted to the medical dressing breaks up the cell structure of the material and the oil is released

Methodology Applied
Scientific EffectPressure-induced release: Compression

Implementation Method 3

The matrix comprises one or more cellulose derivatives and nanocellulose

Methodology Applied
Scientific EffectColloidal dispersion: Colloid

Implementation Method 4

a composite material comprising oil droplets dispersed in a matrix

Methodology Applied
Scientific EffectMatrix stabilization:

Implementation Method 5

the composite material will also, in contact with wound exudates, redisperse into a liquid phase such that the oil comprised in the emulsion is released

Methodology Applied
Scientific EffectPhase transition: Phase Change

Data Source

PatentUS11173228B2Medical dressing comprising a carrier and a composite material
Publication Date: 2021.11.16 MOLNLYCKE HEALTH CARE AB
  • US11173228B2 patent drawing
  • US11173228B2 patent drawing
  • US11173228B2 patent drawing

AI summary

Disclosed is a medical dressing having a carrier material and a composite material. The composite material includes oil droplets dispersed in a matrix. The matrix includes one or more cellulose derivatives and nanocellulose.