Medical Image Analysis via Hierarchical Lesion Data Positioning

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Solution Overview

Problem

Current medical image analysis for breast tissue images is highly subjective and varies significantly between clinicians, due to the low occurrence rate of cancers and the variability in interpreting diverse lesion types, shapes, and characteristics.

Innovation Solution

A method of analysis that involves receiving a breast tissue image, identifying regions of interest, positioning a query image within a hierarchy of lesion data based on tissue characteristics, retrieving statistics from neighboring images, generating analytics, and displaying graphical representations to aid in diagnostic decision-making.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If clinicians evaluate medical images based on subjective interpretation, then diagnostic flexibility is maintained, but diagnostic consistency and accuracy deteriorate due to high variability between clinicians

Engineering Contradiction:
Improvediagnostic flexibilityVSAvoiddiagnostic consistency
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent introduces an intermediary system comprising a hierarchical graph structure and statistical analysis engine that mediates between the medical image data and clinician interpretation. This intermediary processes images through multiple hierarchical levels (super-lesion, lesion, sub-lesion) and provides statistical context about neighboring images, thereby standardizing evaluation while preserving clinician oversight and diagnostic flexibility.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If large-scale medical image data is analyzed to improve diagnostic accuracy, then detection capability improves, but computational complexity and data processing requirements worsen

Engineering Contradiction:
Improvedetection accuracyVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the large-scale medical image database into a hierarchical graph structure organized by anatomical regions, lesion types, and characteristics. This segmentation allows the system to analyze only relevant subsets of data (neighboring images with similar characteristics) rather than processing the entire database, thereby reducing computational complexity while maintaining high detection accuracy through targeted statistical analysis.

Inventive Principle:
Principle #1Segmentation

3Reliability

If diverse lesion types and characteristics are evaluated in detail, then diagnostic comprehensiveness improves, but analysis time and resource requirements worsen

Engineering Contradiction:
Improvediagnostic comprehensivenessVSAvoidanalysis time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent performs preliminary organization of medical images into a hierarchical graph structure during database construction, pre-computing relationships between images based on lesion characteristics, anatomical locations, and histological types. When a new image requires evaluation, the system quickly identifies neighboring images at the same hierarchical level without performing comprehensive analysis of all stored images, thereby reducing analysis time while maintaining diagnostic comprehensiveness.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250029237A1Medical image data analysis and visualization
Publication Date: 2025.01.23 HOLOGIC INC
  • US20250029237A1 patent drawing
  • US20250029237A1 patent drawing
  • US20250029237A1 patent drawing

AI summary

A system and method of analysis for medical image data. An image of breast tissue is received, a region of interest (ROI) in the image is identified based on tissue characteristics, and a query image is defined. A hierarchy of lesion data is retrieved, the hierarchy being formed based on one or more relationships among a plurality of images, and the query image is positioned within the hierarchy of lesion data based on the tissue characteristics. A position of the query image within the hierarchy of the lesion database is determined, identifying one or more neighbor images of the query image from among the plurality of images based on the position, and statistics associated with one or more neighbor images are retrieved. Analytics associated with the query image based on the statistics are generated, and a graphic depicting the analytics is displayed.