Medical Image Segmentation Using Pre-trained Decoder Shape Priors

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Solution Overview

Problem

Current image segmentation technologies face challenges such as domain mismatch and image quality variations, leading to issues like over-segmentation and under-segmentation, particularly in medical imaging, due to practical constraints and complexities.

Innovation Solution

A neural network-based system comprising an encoder and a decoder network, where the decoder network is pre-trained to learn a shape prior associated with anatomical structures, and is used to constrain the output of the encoder network during training, employing iterative training methods and co-training with another encoder network to improve segmentation accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional image segmentation methods are used, then processing speed is maintained, but segmentation accuracy deteriorates due to domain mismatch and image quality variations

Engineering Contradiction:
Improvesegmentation accuracyVSAvoiddomain adaptability
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The decoder network is pre-trained on a large dataset of anatomical structures to learn shape priors and anatomical patterns before being deployed. This preliminary training enables the network to adapt to different domains and image qualities without requiring extensive retraining, thereby improving segmentation accuracy across varying conditions while maintaining domain adaptability

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses iterative training to progressively refine the encoder network's parameters. By changing parameters incrementally through multiple training iterations with the pre-trained decoder as a constraint, the system achieves better segmentation accuracy while adapting to different domains and image variations

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If the decoder network is pre-trained to learn shape prior, then segmentation accuracy is improved, but training time and computational complexity increase

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidtraining time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The decoder network undergoes pre-training on a large dataset to learn shape priors and anatomical patterns before being deployed. This preliminary training enables the network to adapt to different domains and image qualities without requiring extensive retraining, thereby improving segmentation accuracy across varying conditions while maintaining domain adaptability

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system employs iterative training where the encoder and decoder networks are continuously refined together. The pre-trained decoder serves as a persistent constraint throughout the training process, guiding the encoder's parameter optimization continuously rather than through discrete, time-consuming retraining cycles

Inventive Principle:
Principle #20Continuity of useful action

3Manufacturing precision

If iterative training with pre-trained decoder constraint is used, then over-segmentation and under-segmentation are reduced, but device complexity increases

Engineering Contradiction:
Improvesegmentation precisionVSAvoidnetwork architecture complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The encoder and decoder networks are trained together in an integrated iterative process, merging their training cycles. The pre-trained decoder serves as a constraint that guides the encoder's learning, combining shape prior knowledge with image-specific features in a unified training framework that reduces over-segmentation and under-segmentation while managing architectural complexity

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS11488021B2Systems and methods for image segmentation
Publication Date: 2022.11.01 SHANGHAI UNITED IMAGING INTELLIGENCE CO LTD
  • US11488021B2 patent drawing
  • US11488021B2 patent drawing
  • US11488021B2 patent drawing

AI summary

Described herein are neural network-based systems, methods and instrumentalities associated with image segmentation that may be implementing using an encoder neural network and a decoder neural network. The encoder network may be configured to receive a medical image comprising a visual representation of an anatomical structure and generate a latent representation of the medical image indicating a plurality of features of the medical image. The latent representation may be used by the decoder network to generate a mask for segmenting the anatomical structure from the medical image. The decoder network may be pre-trained to learn a shape prior associated with the anatomical structure and once trained, the decoder network may be used to constrain an output of the encoder network during training of the encoder network.