Medical Image Segmentation Using Multi-Parameter MRI Analysis

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Solution Overview

Problem

The segmentation and visualization of medical image data, particularly MRI scans, is a complex task due to noisy data, low contrast images, and large variations between patients, requiring advanced methods to accurately classify pixels into anatomical structures or abnormalities, which existing technologies struggle to efficiently accomplish.

Innovation Solution

A system and method that generates a patient-specific 3D model from two-dimensional medical images using a data-driven approach, incorporating anatomical constraints, shape components, and machine learning algorithms to automate the segmentation process, allowing for the creation of anatomically accurate models and procedural animations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If manual segmentation is used for CT images with threshold values, then segmentation is simpler and faster, but it lacks resolution to differentiate soft tissues

Engineering Contradiction:
Improvesegmentation speedVSAvoidsoft tissue differentiation resolution
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent transitions from intensity-based thresholding to using multiple MRI parameters (T1, T2, proton density) to characterize tissues. This parameter expansion enables soft tissue differentiation by capturing different physical properties of tissues rather than relying solely on signal intensity, thus resolving the contradiction between segmentation speed and soft tissue resolution.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite classification approach by integrating multiple MRI sequences and parameters into a unified segmentation framework. This composite method combines information from T1-weighted, T2-weighted, and proton density images to achieve comprehensive soft tissue characterization, overcoming the limitations of single-parameter thresholding.

Inventive Principle:
Principle #40Composite materials

2Measurement precision

If manual segmentation is used for MRI scans, then soft tissue differentiation is possible, but it requires many hours of work and expensive specialized software

Engineering Contradiction:
Improvesoft tissue differentiation resolutionVSAvoidsegmentation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent implements automated segmentation algorithms that perform tissue classification without requiring manual intervention. The system uses machine learning models trained on MRI data to automatically segment soft tissues, eliminating the need for expert operators and significantly reducing segmentation time while maintaining high precision.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual mechanical segmentation processes with automated computational algorithms. Instead of relying on human experts to manually trace and classify tissues, the system uses computer-based image processing and machine learning to perform segmentation automatically, thus eliminating time loss and reducing dependency on specialized software and expertise.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If automated segmentation algorithms are used, then processing time is reduced, but accuracy decreases due to noisy data and low contrast images

Engineering Contradiction:
Improvesegmentation efficiencyVSAvoidclassification accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent applies preliminary image preprocessing steps including noise filtering, contrast enhancement, and registration before segmentation. These preliminary actions prepare the noisy, low-contrast MRI images by reducing artifacts and improving signal-to-noise ratio, thereby enabling automated algorithms to achieve high accuracy without manual intervention.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements iterative refinement processes where segmentation results are evaluated and fed back into the algorithm for improvement. The system uses feedback from intermediate classification results to adjust parameters and re-segment ambiguous regions, progressively improving accuracy while maintaining automated efficiency throughout the process.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12073528B2System and method for segmentation and visualization of medical image data
Publication Date: 2024.08.27 MULTUS MEDICAL LLC
  • US12073528B2 patent drawing
  • US12073528B2 patent drawing
  • US12073528B2 patent drawing

AI summary

A computing device has a processor. A display is coupled to the processor. A user interface is coupled to the processor for entering data into the computing device. A memory is coupled to the processor, the memory storing program instructions that when executed by the processor, causes the processor to: generate a patient specific three-dimensional model of an anatomical area from two-dimensional data images of the anatomical area; load a patient procedure and/or surgery report; add procedural instruments and/or devices to be used based on the patient procedure and/or surgery report; and create a medical procedural animation from the patient specific three-dimensional model and the procedural instruments and/or devices.