Surfactant-Free Medical Instrument Cleaning Composition

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Solution Overview

Problem

Existing cleaning compositions for medical instruments often produce foam during automated washing, which can hinder cleaning efficacy, especially in high-agitation environments, and may contaminate instruments with defoaming agents or require surfactants that are not compatible with all medical instrument materials.

Innovation Solution

A surfactant-free cleaning composition comprising alkanolamines, mineral acids, hydroxycarboxylic acid salts, and protease enzymes, which produces little to no foam and effectively removes biological soils without surfactants, maintaining a neutral pH suitable for medical instruments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surfactants are used to remove biological soils, then cleaning efficacy is improved, but foam is produced which hinders cleaning in high-agitation environments

Engineering Contradiction:
Improvecleaning efficacyVSAvoidfoam
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The invention extracts and removes surfactants from the cleaning composition entirely, replacing them with alternative active substances (enzymes, alkanolamines, mineral acids, hydroxycarboxylic acid salts) that do not produce foam. This eliminates the harmful foam effect while maintaining cleaning capability through different mechanisms.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the chemical parameters of the cleaning system by using enzymes, alkanolamines, and mild acids instead of traditional surfactants. This parameter change fundamentally alters the cleaning mechanism from surfactant-based emulsification to enzyme-based degradation and acid-based dissolution, eliminating foam production.

Inventive Principle:
Principle #35Parameter changes

2Object-generated harmful factors

If foam control agents such as silicone oils are added to reduce foam, then foam is reduced, but the surfaces of medical instruments become contaminated with the defoamer

Engineering Contradiction:
ImprovefoamVSAvoidsurface contamination
Core Design Contradiction:
Object-generated harmful factorsVSObject-affected harmful factors

Solution Approach 1:

The invention extracts and eliminates the need for separate foam control agents by using a surfactant-free formulation. Since no surfactants are present to generate foam, no additional defoaming agents are required, thereby avoiding surface contamination from silicone oils or other defoamers.

Inventive Principle:
Principle #2Taking out (Extraction)

3Object-generated harmful factors

If highly alkaline surfactant-free detergent systems are used to prevent foaming, then foam is eliminated, but materials compatibility issues arise with aluminium and anodised aluminium instruments

Engineering Contradiction:
ImprovefoamVSAvoidmaterial compatibility
Core Design Contradiction:
Object-generated harmful factorsVSObject-affected harmful factors

Solution Approach 1:

The invention changes the pH parameter from highly alkaline to essentially neutral by using alkanolamines (which provide mild alkalinity) combined with mineral acids and hydroxycarboxylic acid salts. This parameter adjustment maintains foam-free operation while ensuring compatibility with aluminium and anodised aluminium instruments.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite cleaning system combining multiple substances (enzymes, alkanolamines, mineral acids, hydroxycarboxylic acid salts) that work synergistically to achieve foam-free cleaning at neutral pH, replacing the single-component highly alkaline surfactant-free systems.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively removes biological soils from medical instruments, avoiding foam issues and material compatibility problems, with enhanced cleaning efficacy and no surfactant-related contamination, making it suitable for automated washing processes.

Implementation Method 1

at least one protease enzyme

Methodology Applied
Scientific EffectEnzymatic degradation: Enzyme

Implementation Method 2

at least one alkanolamine, at least one mineral acid

Methodology Applied
Scientific EffectAcid-base neutralization: Chemical Bonding

Implementation Method 3

at least one salt of a hydroxycarboxylic acid

Methodology Applied
Scientific EffectChelation: Chemical Bonding

Data Source

PatentEP3256564B1Detergent for medical instrumentation
Publication Date: 2019.09.04 WHITELEY CORPORATION PTY LTD

AI summary

A cleaning composition comprising: a. At least one alkanolamine b. At least one mineral acid c. At least one salt of a hydroxycarboxylic acid d. At least one protease enzyme; wherein said composition contains no surfactant.