Anonymous Medical Rule Aggregation System

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Solution Overview

Problem

The existing evidence-based approach to determining medical knowledge is slow, making it difficult to adapt to time-varying phenomena and leading to delayed identification and correction of errors, which can adversely impact patient health and trust.

Innovation Solution

A computer system dynamically generates population-based medical rules by iteratively applying and aggregating local medical rules across anonymous sub-populations without sharing Protected Health Information (PHI), using quality metrics to modify and provide the rules to users, enabling continuous adaptation and improvement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If clinical trials and peer-reviewed publication are used to determine medical knowledge, then reliability of medical knowledge is improved, but time required to generate and update medical knowledge increases

Engineering Contradiction:
Improvereliability of medical knowledgeVSAvoidtime required to generate and update medical knowledge
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent segments the population-based medical rule validation process into multiple independent sub-populations. Each sub-population can be analyzed separately using the same local medical rule, allowing parallel processing and faster aggregation of results across diverse populations without requiring sequential clinical trials

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies preliminary action by using retrospective analysis on existing medical records before prospective application. Local medical rules are first validated against historical data from multiple sub-populations to assess performance metrics, and only after successful validation are the rules prospectively applied to guide clinical decisions, reducing the time needed for full clinical trial validation

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If local medical rules are applied across multiple sub-populations to generate population-based medical rules, then accuracy of medical knowledge is improved, but complexity of the system increases

Engineering Contradiction:
Improveaccuracy of medical knowledgeVSAvoidcomplexity of the system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements universality by designing a multi-functional computer system that can perform multiple operations: retrieving medical records, applying local medical rules, calculating performance metrics, aggregating results across sub-populations, and generating population-based medical rules. This single system handles the entire workflow, reducing overall system complexity compared to separate systems for each function

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent uses an intermediary approach by introducing a computer system that acts as a mediator between local medical rules and population-based medical rule generation. The computer system aggregates results from multiple sub-populations and applies quality metrics to determine when population-based rules should be generated, simplifying the complex process of cross-population validation

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If medical rules are updated rapidly to adapt to time-varying phenomena, then adaptability of medical knowledge is improved, but risk of errors increases

Engineering Contradiction:
Improveadaptability of medical knowledgeVSAvoidrisk of errors in medical knowledge
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent implements feedback mechanisms by continuously monitoring the performance of local medical rules across multiple sub-populations using quality metrics. The system aggregates results and uses this feedback to determine when population-based medical rules should be generated, ensuring that rapid updates are based on validated performance data rather than unverified changes

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent applies dynamics by making the medical rule validation and update process dynamic rather than static. The system can adaptively determine when to generate population-based medical rules based on aggregated performance metrics from sub-populations, allowing medical knowledge to evolve rapidly in response to changing conditions while maintaining reliability through continuous validation

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS10964412B2Population-based medical rules via anonymous sharing
Publication Date: 2021.03.30 Q BIO INC
  • US10964412B2 patent drawing
  • US10964412B2 patent drawing
  • US10964412B2 patent drawing

AI summary

A computer system may iteratively modify a local medical rule that is based on an initial sub-population. In particular, after information specifying the local medical rule and sharing instructions are received from a user of the computer system, the computer system may iteratively apply the local medical rule to one or more additional sub-populations that are associated with other users of the computer system based on the sharing instructions without sharing PHI associated with the initial sub-population. Then, the computer system may aggregate results for the one or more additional sub-populations, and may generate the population-based medical rule by modifying the local medical rule based on the aggregated results and one or more quality metrics. Moreover, the computer system may selectively provide the population-based medical rule to the user without sharing PHI associated with the one or more additional sub-populations.