Medicament Applicator Dispenser Capillary Retention Dosing Accuracy
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Solution Overview
Problem
Existing applicators for treating skin lesions lack the accuracy and safety in delivering a precise dose of medicament to the target area, often resulting in excessive exposure to surrounding healthy tissue.
Innovation Solution
A medicament applicator with a dispenser that utilizes capillary forces to retain and deliver a predetermined volume of liquid medicament, featuring non-deformable structures such as grooves or cavities, which ensures accurate and safe application by preventing runoff and facilitating tissue penetration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional topical applicators are used to deliver pharmaceutical compositions, then the treatment can be applied to skin lesions, but the dosing accuracy and coverage are insufficient, resulting in excessive exposure to surrounding healthy tissue
Solution Approach 1:
The dispenser surface is segmented into multiple discrete structures (protrusions, cavities, grooves, or pillars) that each hold a controlled volume of medicament. This segmentation allows precise delivery of medicament only to specific contact points on the skin lesion, preventing runoff to surrounding healthy tissue while ensuring adequate coverage of the target area
Solution Approach 2:
The applicator head features localized medicament retention structures with specific geometries designed to hold and release medicament at precise locations. Each structure is optimized to retain a predetermined volume of liquid medicament and release it upon contact with the skin, ensuring that medicament is delivered only where the applicator contacts the lesion and not to surrounding areas
2Reliability
If a sufficient amount of tissue-ablative composition is delivered to effectively remove skin lesion tissue, then the treatment effectiveness is improved, but the risk of exposing surrounding healthy tissue increases
Solution Approach 1:
The dispenser structures are pre-configured to hold a predetermined volume of liquid medicament before application. This preliminary retention ensures that the exact amount of medicament needed for effective treatment is available at the point of application, and the controlled release upon contact prevents both under-dosing (ineffective treatment) and over-dosing (exposure of healthy tissue)
3Measurement precision
If the applicator delivers a predetermined volume of medicament (1 μL to 100 μL), then the dosing precision is improved, but the device complexity increases
Solution Approach 1:
The dispenser structures utilize the inherent capillary properties of their geometric features (protrusions, cavities, grooves, or pillars) to automatically retain and release the predetermined volume of liquid medicament. The capillary forces within these structures self-regulate the medicament volume, eliminating the need for complex mechanical dosing mechanisms, pumps, or electronic controls while achieving precise dose delivery
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The applicator effectively delivers a precise dose of medicament to skin lesions, minimizing exposure to healthy tissue and ensuring safe and effective treatment of benign or malignant lesions.
Implementation Method 1
The plurality of non-deformable structures are configured for retaining a predetermined volume of a liquid medicament delivered from the container
Implementation Method 2
The delivery of at least said part of the predetermined volume of the medicament to the surface upon contact therewith is effected via capillary transfer
Data Source
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AI summary
The present invention provides an applicator for administration of a medicament, comprising a container being in fluid communication with a dispenser having a plurality of non-deformable structures configured for retaining a predetermined volume of a liquid medicament delivered from said container, said dispenser being capable of delivering at least a part of said predetermined volume of said liquid medicament to a surface upon contact therewith.