Medicament Delivery Device Segmented Drive for Safe Reconstitution
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Solution Overview
Problem
Existing medicament delivery devices often fail to ensure complete and uninterrupted mixing of medicament and diluent agents before delivery, risking accidental administration of unreconstituted medicament.
Innovation Solution
A medicament delivery device with a movable medicament delivery drive unit that separates from the actuation mechanism, ensuring complete mixing before allowing delivery, by transitioning from a first to a second position, thereby preventing accidental activation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the medicament delivery drive unit is integrated with the actuator, then the device structure is compact, but accidental delivery may occur before mixing is complete
Solution Approach 1:
The device is divided into separate functional modules: the medicament delivery drive unit is separated from the actuator. The drive unit includes a piston for mixing while the actuator is dedicated to delivery activation. This segmentation ensures that mixing completion must be detected before the actuator can engage the drive unit, preventing accidental delivery.
Solution Approach 2:
The mixing action is performed as a preliminary step before delivery can be activated. The drive unit must complete the mixing cycle and be detected in its retracted position before the actuator can engage to perform delivery. This preliminary action sequence ensures mixing is complete before administration.
2Reliability
If the actuator can engage the drive unit at any position, then delivery can be activated quickly, but unreconstituted medicament may be administered
Solution Approach 1:
A detection mechanism monitors the position of the medicament delivery drive unit and provides feedback control. The actuator is enabled to engage the drive unit only when the detection mechanism confirms the drive unit has reached its retracted position, indicating mixing completion. This feedback control ensures mixing is complete before delivery activation is permitted.
Solution Approach 2:
The engagement capability of the actuator is made dynamic rather than static. The actuator transitions from a disabled state to an enabled state based on the drive unit position. This dynamic control allows quick activation once mixing is complete while preventing premature activation during mixing.
3Ease of operation
If the drive unit remains in the first position, then the device is ready for immediate delivery, but mixing may be incomplete
Solution Approach 1:
A detection mechanism acts as an intermediary between the drive unit position and the actuator engagement. This intermediary verifies that the drive unit has reached the retracted position indicating mixing completion before allowing the actuator to engage. This intermediary ensures reliability while maintaining ease of operation through automatic verification.
Data Source
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AI summary
A medicament delivery device for a reconstituted medicament, comprising a proximal housing part (12; 12''; 12'''), a distal housing part (10; 10''; 10'''), a medicament delivery drive unit and actuation means, wherein the medicament delivery drive unit is mounted in said distal housing part and wherein the actuation means further include an activation member (74; 101; 201) which is displaceable between an inactive position wherein the actuator is prevented from engaging the medicament delivery drive unit and an active position wherein the actuator is able to engage the medicament delivery drive, whereby the actuator is capable of interacting with said medicament delivery drive unit to perform a delivery of the reconstituted medicament only in the active position of the activation member and in the second position of the medicament delivery drive unit.