Medicament Proportioning Module With Purified Water Flow Control

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Solution Overview

Problem

Existing medical fluid preparation systems for home use face challenges in providing safe and precise medicament mixing without the need for large-scale water purification systems, which are impractical and require complex installation and maintenance.

Innovation Solution

A compact medicament preparation system comprising a water purification module and a medicament proportioning module, integrated with a replaceable fluid circuit, that ensures safe and precise medicament mixing using a controller to regulate fluid flow and proportioning, allowing operation in home or critical care environments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If large reverse osmosis plants are used for water purification in home dialysis, then purified water supply is achieved, but system complexity and installation requirements increase significantly

Engineering Contradiction:
Improvepurified water supplyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts the water purification function from the complex reverse osmosis system and implements it through a simpler alternative using purified water containers. This allows home dialysis systems to obtain purified water without requiring large-scale reverse osmosis plants, thereby reducing system complexity while maintaining water purification reliability.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs disposable purified water containers as a temporary but effective solution for water purification. These pre-purified water containers eliminate the need for complex permanent purification systems in home settings, providing reliable purified water supply through simpler, replaceable units.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If large reverse osmosis plants are installed for home dialysis, then purified water is provided, but installation and maintenance difficulty increase

Engineering Contradiction:
Improvepurified water supplyVSAvoidinstallation and maintenance
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent separates the water purification requirement from the dialysis machine itself, using external purified water containers. This extraction approach allows the dialysis system to function with pre-purified water without requiring complex purification infrastructure, significantly easing installation and maintenance requirements.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

By using disposable purified water containers, the patent eliminates the need for complex installation and maintenance of permanent purification systems. The containers are pre-prepared and simply connected to the dialysis machine, making the system easy to install and maintain while ensuring reliable purified water supply.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Reliability

If precise medicament mixing systems are implemented, then treatment safety is improved, but system complexity and cost increase

Engineering Contradiction:
Improvetreatment safetyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the medicament mixing function into separate, dedicated mixing chambers within the fluid circuit. Each chamber is designed for specific mixing purposes with appropriate volume and configuration, allowing precise medicament mixing through modular components rather than a single complex mixing system.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent incorporates pre-configured mixing chambers with predetermined volumes and configurations optimized for specific medicament mixing requirements. These chambers are prepared in advance during system manufacturing, eliminating the need for complex real-time adjustment mechanisms and reducing overall system complexity while maintaining treatment safety.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables safe, reliable, and efficient medicament preparation with minimal infrastructure requirements, ensuring precise medicament mixing and reducing the need for specialized installation and maintenance.

Implementation Method 1

water purification module

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

medicament proportioning module... precisely proportion the net amounts of fluid supplied and discharged

Methodology Applied
Scientific EffectProportioning:

Implementation Method 3

controller to regulate fluid flow and proportioning... monitoring of pressure, temperature, leaks, and other treatment conditions

Methodology Applied
Scientific EffectFlow regulation:

Data Source

PatentUS12390568B2Medicament preparation and treatment devices, methods, and systems
Publication Date: 2025.08.19 NXSTAGE MEDICAL INC
  • US12390568B2 patent drawing
  • US12390568B2 patent drawing
  • US12390568B2 patent drawing

AI summary

A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.