Medicated Module with User Selection for Dual Medicament Delivery

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Solution Overview

Problem

Current drug delivery systems face challenges in efficiently and safely administering multiple medicaments, particularly in combination therapies where stability and therapeutic ratios are critical, often requiring complex calculations and multiple delivery systems, which can be cumbersome for users with dexterity or computational difficulties.

Innovation Solution

A medicated module with a single dose setting mechanism and dispense interface allows for the simultaneous delivery of two or more medicaments from separate reservoirs, where setting the dose of one medicament automatically determines the dose of another, enabling variable dosing and bypass options through a user-friendly selector mechanism.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple separate delivery systems are used to administer multiple medicaments, then dosing flexibility and therapeutic optimization are improved, but device complexity and user burden increase significantly

Engineering Contradiction:
Improvedosing flexibilityVSAvoidnumber of delivery systems
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent combines multiple medicament delivery systems into a single integrated device that can administer multiple medicaments through one injection site. The device includes multiple reservoirs (first and second medicament reservoirs) that can be simultaneously connected to a single dispensing mechanism, allowing both medicaments to be delivered in one action without requiring separate injection systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The single dispensing mechanism serves multiple functions by being capable of dispensing both the first medicament from the first reservoir and the second medicament from the second reservoir. The mechanism can selectively connect to different reservoirs or both simultaneously, providing universal dosing capability for multiple drug compounds through one interface.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If multiple separate delivery systems are used to administer multiple medicaments, then dosing flexibility is improved, but ease of operation deteriorates due to increased user complexity

Engineering Contradiction:
Improvedosing flexibilityVSAvoiduser operation simplicity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The patent combines multiple medicament delivery systems into a single integrated device that can administer multiple medicaments through one injection site. The device includes multiple reservoirs (first and second medicament reservoirs) that can be simultaneously connected to a single dispensing mechanism, allowing both medicaments to be delivered in one action without requiring separate injection systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device incorporates automatic dosing mechanisms where the control system automatically calculates and dispenses the correct doses of multiple medicaments based on pre-programmed parameters. The system handles the complexity of dose calculation and coordination between multiple reservoirs automatically, reducing the operational burden on the user while maintaining dosing flexibility.

Inventive Principle:
Principle #25Self-service

3Ease of operation

If pre-mixed formulations of multiple active agents are used, then delivery simplicity is improved, but adaptability deteriorates due to fixed ratio constraints

Engineering Contradiction:
Improvedelivery simplicityVSAvoiddose ratio variability
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The patent divides the medicament delivery system into separate reservoirs for different medicaments, allowing independent control of each component. The first medicament reservoir and second medicament reservoir are physically separated, enabling independent dosing and flexible ratio adjustment while maintaining simple operation through a unified dispensing interface.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system provides dynamic dose adjustment capability where the ratios of different medicaments can be varied based on user needs and therapeutic requirements. The dispensing mechanism can be configured to deliver different proportions of first and second medicaments, allowing the system to adapt to different therapeutic scenarios while maintaining operational simplicity.

Inventive Principle:
Principle #15Dynamics

4Reliability

If separate storage containers for multiple active agents are used, then therapeutic optimization is improved, but device complexity increases

Engineering Contradiction:
Improvetherapeutic optimizationVSAvoidnumber of reservoirs and mechanisms
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple medicament delivery systems into a single integrated device that can administer multiple medicaments through one injection site. The device includes multiple reservoirs (first and second medicament reservoirs) that can be simultaneously connected to a single dispensing mechanism, allowing both medicaments to be delivered in one action without requiring separate injection systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The single dispensing mechanism serves multiple functions by being capable of dispensing both the first medicament from the first reservoir and the second medicament from the second reservoir. The mechanism can selectively connect to different reservoirs or both simultaneously, providing universal dosing capability for multiple drug compounds through one interface.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP2550043B1Medicated module with user selection
Publication Date: 2017.10.11 SANOFI AVENTIS DEUT GMBH
  • EP2550043B1 patent drawingFigure 1~2
  • EP2550043B1 patent drawingFigure 3
  • EP2550043B1 patent drawingFigure 4

AI summary

A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle (3). The medicated module (4) is user selectable so that it will deliver a priming dose of a primary medicament or both the primary and secondary medicaments. The module (4) also contains a needle guard (42) that locks after dose delivery. The needle guard (42) prevents accidental needle sticks before and after an injection. A locking collar (66) rotates during use as an inner protrusion (12) follows three paths (14, 15, 16) of a track (13) located on the outer surface of a body housing (10). When the inner facing protrusion (12) is in the third path (16), it encounters a hard stop and a rotational bias that locks the guard (42) from further retraction and thus covers the sharp distal end of the needle (3).