Medicated Module with User-Selectable Dual Drug Delivery
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current drug delivery systems face challenges in administering complex combinations of multiple drug compounds, particularly in combination therapy where stability and therapeutic ratios are critical, and users with dexterity or computational difficulties struggle to accurately set and deliver correct doses of multiple medicaments.
Innovation Solution
A medicated module and drug delivery system that allows for the administration of multiple drug compounds through a single dose setting mechanism and dispense interface, enabling separate storage and combination of drug agents only at the point of delivery, with a selector to choose between combined or single medicament delivery, and adjustable dosing to accommodate varying therapeutic needs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If separate storage containers for multiple drug agents are used, then drug stability and therapeutic ratios are improved, but device complexity and user operation difficulty increase
Solution Approach 1:
The patent combines multiple separate drug delivery functions into a single integrated device. The first and second reservoirs are housed within one device with a unified dose setting mechanism that controls both drug delivery operations, merging what would traditionally require separate devices into one cohesive system that maintains drug stability while reducing operational complexity
Solution Approach 2:
The device employs a universal dose setting mechanism that serves multiple functions: it controls the dose of the first drug agent directly, automatically determines the dose of the second drug agent based on the first drug's dose, and can bypass the second drug reservoir when needed. This multi-functional mechanism eliminates the need for separate controls for each drug, simplifying the device while maintaining reliability
2Reliability
If separate storage containers for multiple drug agents are used, then drug stability is improved, but ease of operation deteriorates
Solution Approach 1:
The device performs automatic dose determination for the second drug agent based on the dose of the first drug agent set by the user. The dose setting mechanism automatically calculates and sets the appropriate dose for the second drug, eliminating the need for users to perform separate calculations or adjustments, thereby maintaining drug stability while significantly improving ease of operation
Solution Approach 2:
Instead of requiring users to independently set doses for multiple drugs, the system inverts the approach by having the user set only the first drug's dose, with the system automatically determining the second drug's dose. This reversal of the traditional multi-step process simplifies user interaction while preserving the benefits of separate drug storage
3Ease of operation
If a single dose setting mechanism controls multiple drugs, then ease of operation is improved, but adaptability to different dosing regimens deteriorates
Solution Approach 1:
The device incorporates a dynamic bypass mechanism that allows the second drug reservoir to be selectively connected or disconnected from the delivery path. This dynamic configuration enables the device to adapt between different dosing regimens: delivering both drugs when needed, or bypassing the second drug when a single-drug regimen is required, all while maintaining ease of operation through the unified dose setting mechanism
Data Source
AI summary
A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments are delivered through a single hollow needle (5). The medicated module (4) is user selectable so that it will deliver both the primary (1) and secondary medicaments (2), or only the primary medicament (1). The module (4) also contains a guard (42) that locks after dose delivery.