Medicated Module Linkage Mechanism for Variable Dose Ratios
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Solution Overview
Problem
Current drug delivery systems face challenges in simultaneously administering multiple drug agents with specific dosage ratios, as pre-mixed formulations are inflexible and require complex user calculations, which can be difficult for patients with dexterity or computational issues, and may lead to incorrect dosing.
Innovation Solution
A drug delivery system with separate reservoirs for multiple drug agents, allowing for a single dispense interface that automatically sets the dose of one medicament, thereby determining the dose of another, enabling variable and fixed dose profiles through a mechanism with a collar and linkage component, simplifying the administration process.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If pre-mixed formulations of multiple active agents are used, then the device structure is simplified, but the dosage ratio becomes fixed and cannot be varied for different patients or treatment stages
Solution Approach 1:
The device divides the medication delivery system into separate reservoirs for each active agent (first reservoir for first medicament, second reservoir for second medicament), allowing independent control and variable dosing ratios while maintaining a unified device structure for simplified operation
2Adaptability or versatility
If separate storage containers for multiple active agents are used, then dosage ratios can be varied for different patients, but the process for combining agents becomes complex and requires user calculations
Solution Approach 1:
The device automatically performs the function of combining multiple agents and calculating dosages through its internal mechanism (linkage component connecting dose setting mechanisms), eliminating the need for users to perform complex calculations or manually coordinate multiple delivery systems
Solution Approach 2:
The device merges multiple dose setting mechanisms into a unified system where a single user input (dialing the dose) simultaneously controls the dosing of multiple active agents through a linkage mechanism, simplifying the user interface while maintaining dosage variability
3Adaptability or versatility
If users manually calculate and coordinate multiple drug delivery systems, then dosage flexibility is maintained, but the risk of incorrect dosing increases for patients with dexterity or computational difficulties
Solution Approach 1:
The device incorporates a linkage mechanism that provides mechanical feedback and interlocking between dose setting mechanisms, ensuring that dosage combinations are automatically validated and preventing incorrect dosing through the physical design of the dose setting process
Data Source
AI summary
A drug delivery device having a collar and a linkage component. The drug delivery device includes a variable dose setting mechanism, a fixed dose setting mechanism, a single dose setter, a collar, and a linkage component. The variable dose setting mechanism is operably coupled to a primary reservoir holding a first medicament. The fixed dose setting mechanism is operably coupled to a secondary reservoir holding a second medicament. Further, the single dose setter is operably coupled to the variable dose setting mechanism, and the collar is disposed on the variable dose setting mechanism. Still further, the linkage component is disposed on the fixed dose setting mechanism, wherein the linkage component is capable of engagement with the collar.