Medicated Module Reservoirs for Accurate Multi-Drug Dosing
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Solution Overview
Problem
Current drug delivery systems face challenges in administering multiple medicaments simultaneously, particularly in combination therapy where pre-mixed formulations are not adjustable, require complex user calculations, and involve multiple delivery systems, which can be cumbersome for users with dexterity or computational difficulties.
Innovation Solution
A medicated module with separate reservoirs for multiple drug agents that allows a single dose setting mechanism to automatically determine the dose of one medicament, enabling a single injection or delivery step through a single dispense interface, with a needle guard mechanism that automatically engages the secondary medicament upon activation, reducing user intervention and ensuring accurate dosing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If separate reservoirs for multiple medicaments are used, then dosing accuracy and adjustability are improved, but device complexity increases
Solution Approach 1:
The device is divided into separate reservoirs for primary and secondary medicaments, each with independent control mechanisms. The primary reservoir is user-settable while the secondary reservoir is automatically controlled, allowing precise dosing of each component without requiring the user to manage multiple complex settings.
Solution Approach 2:
A microprocessor control system acts as an intermediary between the user's dose setting input and the multiple reservoirs. When the user sets a dose for the primary medicament, the microprocessor automatically calculates and controls the corresponding dose of the secondary medicament, simplifying the user interface while maintaining dosing accuracy.
2Ease of operation
If a single dose setting mechanism controls multiple medicaments, then ease of operation is improved, but adaptability decreases
Solution Approach 1:
The system allows different dosing parameters to be set for different medicaments. The primary medicament dose is user-adjustable through a dial or button interface, while the secondary medicament dose is automatically determined based on the primary dose setting, enabling flexible adaptation to different treatment protocols while maintaining simple operation.
Solution Approach 2:
The device performs automatic dose calculation and reservoir selection based on the user's input for the primary medicament. The microprocessor system automatically determines the appropriate secondary medicament dose and activates the correct reservoir, eliminating the need for the user to manually configure multiple parameters.
3Reliability
If automatic needle guard engagement is implemented, then reliability is improved, but device complexity increases
Solution Approach 1:
The needle guard is pre-configured to automatically engage with the secondary medicament reservoir upon activation. This preliminary arrangement ensures that the correct reservoir is engaged before the injection process begins, improving reliability without requiring complex real-time decision-making mechanisms.
Solution Approach 2:
The needle guard mechanism is combined with the reservoir activation system. The same mechanical action that advances the needle also triggers the engagement of the secondary medicament reservoir, reducing the number of separate mechanisms while maintaining reliable operation.
Data Source
AI summary
A reservoir assembly for a medicated module includes a primary cavity for holding a medicament, a sump region, and a flexible element. The flexible element is configured to allow for fluid communication between the primary cavity and the sump region during a filling process for the reservoir. Further, the flexible element is configured to prevent fluid communication between the primary cavity and the sump region after the filling process.