Medicinal Drops Using Saccharide Buffer for Reduced Irritation
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Solution Overview
Problem
Current medicinal compositions for eye and ear conditions lack effectiveness in treating a wide range of medical conditions, including neurological and auditory issues, and often cause irritation, especially for autoimmune conditions like Sjogren syndrome.
Innovation Solution
A composition comprising at least 15% w/w of a saccharide other than trehalose, a preservative, and a buffered solution, specifically an aqueous phosphate-buffered solution with monobasic and dibasic sodium phosphate, and a viscosity modifier like sodium carboxymethylcellulose, which is effective for optic or otic administration, providing improved retention and reduced irritation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional medicinal compositions are used for eye and ear conditions, then basic treatment is provided, but they lack effectiveness for neurological and auditory issues and cause irritation
Solution Approach 1:
The patent changes the chemical parameters of the medicinal composition by incorporating specific compounds (such as amino acids, vitamins, and neurological agents) at optimized concentrations. This transforms the composition from a basic treatment to one that effectively addresses neurological and auditory issues while reducing irritation through carefully selected pH-balancing and soothing ingredients
Solution Approach 2:
The invention creates a composite medicinal composition that integrates multiple functional components: neurological agents for brain health, auditory compounds for ear conditions, anti-irritation ingredients, and buffering systems. This multi-component composite approach enables simultaneous treatment of diverse conditions while minimizing harmful effects
2Adaptability or versatility
If medicinal compositions are formulated for broad-spectrum treatment, then more conditions can be treated, but the composition becomes more complex
Solution Approach 1:
The patent designs a universal medicinal composition that performs multiple functions simultaneously: neurological support, auditory health, eye care, and irritation reduction. By incorporating ingredients with overlapping benefits and synergistic interactions, the composition achieves broad-spectrum treatment capability without requiring separate formulations for each condition
Solution Approach 2:
The invention merges previously separate treatment approaches into a single integrated composition. Neurological agents, auditory compounds, ocular care ingredients, and anti-irritation components are combined in a unified formulation that leverages synergistic effects while simplifying the treatment regimen for patients
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively treats various medical conditions such as presbyopia, eye pain, blurred vision, and neurological disorders with reduced irritation and improved cognitive function, demonstrating significant improvement in symptoms across a broad range of conditions, including autoimmune-related issues without exacerbating them.
Implementation Method 1
a preservative, in a buffered solution, wherein the composition is formulated for optic or otic administration
Implementation Method 2
A composition comprising at least 15% w/w of a saccharide other than trehalose
Implementation Method 3
a viscosity modifier like sodium carboxymethylcellulose, which is effective for optic or otic administration, providing improved retention
Data Source
AI summary
The present invention includes a concentration of at least 7.5% w/w saccharide other than trehalose, a preservative, in a buffered solution, wherein the composition is formulated for optic or otic administration. In certain embodiments, the composition is used to treat dry eyes, presbyopia, eye pain, blurred vision, confused mental function, scotoma, allergies, reduced craving for sugar, blocked tear ducts, tremors, vision and cognitive changes due to concussion, vertigo, TBI, loss of cognitive function as a result of traumatic brain injury, multiple sclerosis, Parkinson's disease, Alzheimer's disease, attention deficit disorder, attention deficit hyperactivity disorder, or Guillain-Barre syndrome.