Medicinal Package Odor Reduction Metallic Oxide Desiccant

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Solution Overview

Problem

Medicinal compounds with unpleasant smells pose challenges in patient compliance and double-blind clinical trials due to their odor, and existing methods for reducing smells, such as decomposition, absorption, and masking, are insufficient, especially under changing environmental conditions.

Innovation Solution

A medicinal package incorporating a chemical absorption-type desiccant, specifically a metallic oxide like calcium oxide, is used to effectively reduce odors by absorbing moisture and odorous materials, maintaining equilibrium and preventing desorption during transportation and storage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If synthetic zeolite, silica gel, silica-alumina, or active carbon is used as a desiccant to absorb moisture and odorous materials, then the initial smell reduction is effective, but under changing environmental conditions (temperature, humidity), the absorbed odorous materials can be desorbed, making the smell reduction insufficient

Engineering Contradiction:
Improveunpleasant smellVSAvoidconsistent smell reduction under varying conditions
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent changes the fundamental parameter of the desiccant from physical absorption (reversible) to chemical absorption (irreversible). By using metallic oxides that chemically react with odorous materials through oxidation or other chemical reactions, the system transforms the temporary physical binding into permanent chemical bonding, eliminating desorption issues under varying environmental conditions

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent converts the harmful reversible nature of physical absorption into a beneficial irreversible chemical reaction. The very property that caused the problem (reversibility of absorption) is replaced by its opposite (irreversibility of chemical reaction), turning the weakness of physical absorption into the strength of chemical absorption

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Ease of manufacture

If physical absorption methods are used to remove odorous materials, then the process is simple and the desiccant can be easily replaced, but the absorption capacity decreases under high temperature and humidity conditions

Engineering Contradiction:
Improvesimplicity of desiccant replacementVSAvoidabsorption capacity
Core Design Contradiction:
Ease of manufactureVSQuantity of substance

Solution Approach 1:

The patent changes the absorption mechanism from physical to chemical, fundamentally altering how the desiccant interacts with odorous materials. This parameter change enables the system to maintain high absorption capacity across a wide range of temperatures and humidity levels, as chemical reactions are less sensitive to environmental conditions compared to physical absorption equilibrium

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of a metallic oxide desiccant in the packaging significantly reduces the concentration of unpleasant smells, ensuring patient comfort and maintaining the integrity of double-blind trials by consistently minimizing odor release.

Implementation Method 1

a chemical absorption-type desiccant such as a metallic oxide effectively reduced smells in a medicinal preparation

Methodology Applied
Scientific EffectChemical reaction with moisture: Chemical Bonding

Implementation Method 2

the absorption of moisture or odorous materials to desiccants such as a synthetic zeolite, silica gel, silica-alumina, or an active carbon is a reversible reaction

Methodology Applied
Scientific EffectChemical absorption: Adsorption

Data Source

PatentEP2068812B9Medicinal package
Publication Date: 2012.08.08 TAKEDA PHARMA CO LTD
  • EP2068812B9 patent drawingFigure 1~6

AI summary

The present invention relates to a medicinal package comprising a medicinal preparation capable of giving out smells, a packaging component and a chemical absorption-type desiccant. According to the present invention, a medicinal package wherein unpleasant smells are reduced is provided.