Flexible Membrane Flow Dampener for Low-Rate Pulsation Control
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Solution Overview
Problem
Current pulsation dampeners are heavy, expensive, and unsuitable for single-use or disposable applications, particularly in biopharmaceutical and pharmaceutical processes, and fail to provide sufficient dampening for accurate measurement of low flow rates.
Innovation Solution
A flow dampener composed of polymer materials with flexible membranes, sealed onto body shells, forming elongate grooves to absorb kinetic energy and reduce fluid pulsation, suitable for single-use applications and effective at low flow rates.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If metal dampeners are used to dampen fluid pulsation, then dampening performance is achieved, but weight and cost increase making them unsuitable for single-use applications
Solution Approach 1:
The patent applies disposable polymer dampeners that can be discarded after single use, eliminating the need for heavy reusable metal dampeners. The polymer construction enables cost-effective single-use applications while maintaining adequate dampening performance for the intended lifecycle.
Solution Approach 2:
The patent uses flexible polymer membranes and shells instead of rigid metal structures. The flexibility of the polymer material provides effective pulsation dampening through elastic deformation, achieving the desired dampening performance with significantly reduced weight compared to metal alternatives.
2Reliability
If metal dampeners are used to dampen fluid pulsation, then dampening performance is achieved, but cost increases making them unsuitable for single-use applications
Solution Approach 1:
The patent applies disposable polymer dampeners that can be discarded after single use, eliminating the need for heavy reusable metal dampeners. The polymer construction enables cost-effective single-use applications while maintaining adequate dampening performance for the intended lifecycle.
Solution Approach 2:
The patent replaces expensive metal mechanical dampeners with polymer-based dampening structures. The polymer material provides equivalent or superior dampening performance through viscoelastic properties, significantly reducing manufacturing cost for single-use applications.
3Reliability
If chemical sterilization is used on metal dampeners, then sterilization is achieved, but effectiveness is insufficient for biopharmaceutical applications
Solution Approach 1:
The patent replaces metal dampeners requiring chemical sterilization with polymer dampeners that can be sterilized by gamma irradiation. This substitution enables more effective and simpler sterilization processes suitable for biopharmaceutical applications, eliminating the limitations of chemical sterilization on metal surfaces.
4Reliability
If conventional dampeners are used, then general dampening is achieved, but sufficient dampening for low flow rate measurement is not provided
Solution Approach 1:
The patent uses flexible polymer membranes with optimized thickness and material properties to provide sufficient dampening even at low flow rates. The flexibility allows the membrane to respond to small pressure variations, providing adequate pulsation reduction for accurate low flow rate measurement that conventional rigid dampeners cannot achieve.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The flow dampener achieves high pulsation reduction, enabling accurate flow rate measurement with Coriolis flow sensors, is cost-effective, and can be sterilized using Gamma irradiation, making it suitable for biopharmaceutical and pharmaceutical processes.
Implementation Method 1
As the flow goes through the elongate flow path, the flexible membrane vibrates with the flow and absorbs kinetic energy in the flow
Implementation Method 2
The flexibility of the flexible membrane dampens vibration in the flow
Data Source
Figure 1
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Figure 2B
AI summary
A flow dampener for dampening pulsation in a fluid flow includes a body shell, a flexible membrane, and two flow ports. The body shell has an interior surface and an elongate groove formed on the interior surface. The flexible membrane is sealed to the interior surface of the body shell and covers the elongate groove. In some embodiments, the flexible membrane is over-molded onto the body shell. The flexible membrane cooperates with the elongate groove to form an elongate flow path for the fluid flow. The flexible membrane has a thickness in a range from 0.5 mm to 6 mm. As the membrane is flexible, it vibrates as the fluid flows through the elongate flow path, absorbs kinetic energy in the fluid flow, and thereby dampens pulsation in the fluid flow.